CAS: 119-39-1; Phthalazin-1(2H)-One

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2,3-二氮杂萘置于苯甲腈 N-氧化物体系中,用 苯 用作溶剂,化学反应 3.0H,以45%的收率获得1-(2H)-酞嗪酮
参考文献:二嗪及其苯并衍生物与氧化苯甲腈的反应
标题:二嗪及其苯并衍生物与氧化苯甲腈的反应
摘要:二嗪1和苯并二嗪2与苯甲腈氧化物在回流的苯中的反应为二嗪环和/或衍生自它们的产物提供了区域,位点和立体特异性环加合物.
Doi:10.1016/0040-4020(95)00746-U

专利信息

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:US-7220858-B2
优先权日:2003-12-23
标 题 :Synthesis of hydrazine and chlorinated derivatives of bicyclic pyridazines
发明人：NELSON DEANNA J
权利人:BARBEAU PHARMA INC
摘要:The present invention relates to both a novel method of preparing hydralazine hydrochloride and to a novel method of preparing hydrazine derivatives of compounds containing a pyridazine ring, including, for example, pyridazines, phthalazines and other compounds containing the pyridazine ring.

专利号:US-8350042-B2
优先权日:2008-01-31
标题 :Antiviral compounds for the treatment of HCV infection
发明人：HERMANN THOMAS C; CARNEVALI MAIA
权利人:UNIV CALIFORNIA; HERMANN THOMAS C; CARNEVALI MAIA
摘要:Disclosed are compounds and methods of synthesis of Formula I for the development of antiviral drugs for the treatment of HCV infection.

专利号:US-4331600-A
优先权日:1980-10-31
标 题:Intermediates for the synthesis of phthalimidines
发明人：GOLEC JR FREDERICK A; AUERBACH JOSEPH
权利人:USV PHARMA CORP
摘要:Compounds of the formula wherein, Y and Z are each H, alkyl, halo, alkoxy, trifluoromethyl, hydroxy, alkanoyloxy, or alkanoylamino; X is F, Cl Br or NR1R2 in which R1 and R2 are each hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl or cycloalkyl; and R is H, alkyl, cycloalkyl or aralkyl; and salts thereof. The compounds have utility as anti-hypertensive and diuretic agents and as intermediates for the preparation of other anti-hypertensive and diuretic agents.

专利号:IL-216705-A0
优先权日:2006-10-17
标 题 :Methods of synthesis of phthalazinone derivative and intermediates in the synthesis

专利号:US-9598418-B2
优先权日:2012-12-31
标 题:Substituted phthalazin-1 (2H)-one derivatives as selective inhibitors of poly (ADP-ribose) polymerase-1
发明人：SRIVASTAVA BRIJESH K; DESAI RANJIT C; PATEL PANKAJ R
权利人:CADILA HEALTHCARE LTD
摘要:The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.