CAS: 188813-02-7; 3-Bromo-5-Fluorobenzaldehyde

上下游产品

CAS号216755-56-5 3-溴-5-氟苄醇 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号1435-51-4 1,3-二溴-5-氟苯 | CAS号1068-55-9 异丙基氯化镁 | CAS号216755-56-5 3-溴-5-氟苄醇 | CAS号627526-90-3 1-溴-3-二氟甲基-5-氟苯

1-溴-3-二氟甲基-5-氟苯置于二乙胺基三氟化硫体系中,用 二氯甲烷 用作溶剂,化学反应 16.0H,以60%的收率获得3-溴-5-氟苯甲醛
参考文献: Heteroaryl Substituted Heterocyclyl Sulfones[fr] Sulfones à Hétérocyclyles à Substitution Hétéroaryle
标题: Heteroaryl Substituted Heterocyclyl Sulfones[fr] Sulfones à Hétérocyclyles à Substitution Hétéroaryle
摘要:这项发明涉及芳基取代的杂环磺酮作为电压门控钙通道阻滞剂,以及含有这些化合物的药物组合物,还涉及这些化合物用于治疗和/或预防疼痛以及其他疾病和/或紊乱.

专利信息

专利号:US-9744252-B2
优先权日:2011-08-17
标 题:Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi
发明人：BERGER MARKUS; KRUGER MARTIN; LOHRKE JESSICA; REINHARDT MICHAEL; SIEBENEICHER HOLGER
权利人:PIRAMAL IMAGING SA
摘要:The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein IIb/IIIa antagonists for imaging of thrombi.

专利号:US-12227528-B2
优先权日:2017-11-09
标 题:Glucose-sensitive albumin-binding derivatives
发明人：KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
权利人:NOVO NORDISK AS
摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.

专利号:US-8378104-B2
优先权日:2010-02-11
标 题 :7-aminofuropyridine derivatives
发明人：HORNBERGER KEITH R; BERGER DAN M; CHEN XIN; CREW ANDREW P; DONG HANQING; KLEINBERG ANDREW; LI AN-HU; MA LIFU; MULVIHILL MARK J; PANICKER BIJOY; SIU KAM W; STEINIG ARNO G; TARRANT JAMES G; WANG JING; WENG QINGHUA; SANGEM RAJARAM; GUPTA RAMESH C
权利人:OSI PHARMACEUTICALS LLC; HORNBERGER KEITH R; BERGER DAN M; CHEN XIN; CREW ANDREW P; DONG HANQING; KLEINBERG ANDREW; LI AN-HU; MA LIFU; MULVIHILL MARK J; PANICKER BIJOY; SIU KAM W; STEINIG ARNO G; TARRANT JAMES G; WANG JING; WENG QINGHUA; SANGEM RAJARAM; GUPTA RAMESH C
摘要:Compounds of Formula 1, as shown below and defined herein: n n n n n n n n n n n n pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by TAK1 or for which an appropriate TAK1 inhibitor is effective. This Abstract is not limiting of the invention.