CAS: 5332-06-9; 4-Bromobutanenitrile

相似化合物

2623-87-2 5414-21-1 6621-59-6

上下游产品

CAS号13064-64-7 2,5-二碘-1,4-苯二醇 | CAS号151-50-8 氰化钾 | CAS号109-64-8 1,3-二溴丙烷 | CAS号628-20-6 4-氯丁腈 | CAS号143-33-9 氰化钠 | CAS号109-70-6 1-溴-3-氯丙烷 | CAS号64-17-5 乙醇 | CAS号42879-03-8 4-bromo-but-2-e... | CAS号141-78-6 乙酸乙酯 | CAS号542-32-5 DL-2-氨基己二酸 | CAS号5336-75-4 4-(二乙氨基)丁腈 | CAS号5048-25-9 6-庚烯腈 | CAS号1859-29-6 4-[2-cyanoethyl... | CAS号21994-40-1 Butanenitrile, ... | CAS号19157-86-9 Butanenitrile,4... | CAS号2046-18-6 4-苯基丁腈 | CAS号119-61-9 二苯甲酮 | CAS号10413-00-0 Benzenepentanen... | CAS号119-53-9 2-羟基-2-苯基苯乙酮

4-氯丁腈置于lithium Bromide体系中,用 Various Solvent(S) 作为反应溶剂,化学反应 2.0H,反应生成 4-溴丁腈
参考文献:一种将伯烷基氯转化为高纯度溴化物 (>=99%) 的便捷实用方法
标题:一种将伯烷基氯转化为高纯度溴化物 (>=99%) 的便捷实用方法
摘要:摘要置于3-戊酮中用 10 当量(各)溴化锂在 120oc 下重复处理(水处理后的第二次)伯烷基氯化物总共 5 小时,得到相应的溴化物,收率极好(86-96 %) 和高化学纯度 (>=99%).
DOI:10.1080/00397919408012653

专利信息

专利号:WO-9419366-A1
优先权日:1993-02-26
标题 :Chemical synthesis of squalamine
发明人：MORIARTY ROBERT M; GUO LIANG; TULADHAR SUDERSAN M
权利人:MAGAININ PHARMA
摘要:Methods for the chemical preparation or synthesis of the sterol antibiotic squalamine. Preferably, the preparation is by modifying the 3-position of a 3-oxo-7α-hydroxy-24z-ether protected alcohol group-5α-cholestane with a spermidino moiety to form a 3β-spermidino-7α-hydroxy-24z-ether protected group -5α-cholestane; deprotecting the 24-position of the 3β-spermidino-7α-hydroxy-24z-ether protected group-5α-cholestane to the free hydroxyl; and sulfating the 24-position of the 3β-spermidino-7α, 24-dihydroxy-5α-cholestane.

专利号:WO-2024174285-A1
优先权日:2023-02-21
标题:Method for preparing halogenated compound from metal halide salt on basis of mobile phase
发明人：SU REN; Ye Jiani
权利人:UNIV SOOCHOW
摘要:Disclosed is a method for preparing a halogenated compound from a metal halide salt on the basis of a mobile phase. The method comprises: converting an aromatic hydrocarbon, alkane or nitrile compound into a halogenated compound by means of a cheap metal halide salt and a photocatalyst under illumination. The method uses a cheap and safe halide salt as a halogen source, does not introduce additional elemental halogen or an additional oxidant, can implement a reaction at normal temperature and normal pressure, is high in terms of selectivity and friendly to environment, and can be used for replacing an existing synthesis reaction system for halogenated compounds. A mobile phase device is used to replace a tank reactor, such that operation is easy and convenient, the price is low, the substrate adaptability is high, the continuous synthesis of halogenated compounds can be achieved, and the method is suitable for industrial large-scale production.

专利号:US-8506927-B2
优先权日:2011-01-05
标 题 :Pegylated fluorobenzamide analogues, their synthesis and use in diagnostic imaging
发明人：MACH ROBERT H; TU ZHUDE
权利人:MACH ROBERT H; TU ZHUDE; UNIV WASHINGTON
摘要:Pegylated fluoroalkoxybenzamide compounds which selectively bind Sigma-2 receptors are disclosed. These compounds, when labeled with a positron-emitting radioisotope such as 18 F, can be used as radiotracers for medical imaging such as imaging of tumors by positron emission tomography (PET). In addition, these compounds, when labeled with 123 I, can be used as radiotracers for imaging of tumors by single photon emission computed tomography (SPECT). Methods for synthesis of these compounds are also disclosed.

专利号:EP-0468457-B1
优先权日:1990-07-24
标题 :Novel substituted piperidines and their use as inhibitors of cholesterol synthesis
发明人：MCCARTHY JAMES R; BARNEY CHARLOTTE L; WANNAMAKER MARION W
权利人:MERRELL DOW PHARMA
摘要:The present invention relates to a group of compounds which are novel substituted piperidines and which act to inhibit the synthesis of cholesterol in mammals and in fungi.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-2004116724-A1
优先权日:1996-12-06
标 题:Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
发明人：KINNEY WILLIAM A; JONES STEVEN; ZHANG XUEHAI; RAO MEENA N; BULLIARD MICHEL; MECKLER HAROLD; LEE NANCY
摘要:A method is described for stereoselectively reducing an unsaturated alkyl ketone substituent attached to a fused ring base. In this method, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent. This reaction stereoselectively reduces the unsaturated alkyl ketone to an unsaturated alkyl alcohol. The unsaturated alkyl alcohol can be further reduced, if desired, to produce a saturated alkyl alcohol. The fused ring base can be, for example, a steroid ring base or a base of a vitamin D analog. The process in accordance with the invention can be used with an alkeneone substituent (e.g., a 22-ene-24-one substituent) or an alkyneone substituent (e.g., a 22-yne-24-one substituent) on a steroid ring base to make squalamine or other useful aminosterol compounds and intermediates for making aminosterol compounds.