专利号:WO-9517903-A1 优先权日:1993-12-28 标 题:Modular design and synthesis of oxazolone-derived molecules 发明人:HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.
专利号:US-8067633-B2 优先权日:2006-12-05 标 题:Method for the synthesis of (meth)acrylic esters catalysed by a polyol titanate 发明人:PAUL JEAN-MICHEL 权利人:PAUL JEAN-MICHEL; ARKEMA FRANCE 摘要:The subject of the invention is a method for the synthesis of (meth)acrylic esters by transesterification in the presence of a catalyst corresponding to the formula [(R′O) 3 Ti] x R″ in which R′ is a linear or branched alkyl radical having from 2 to 8 carbon atoms which may contain heteroatoms or R′ is a phenyl radical, R′ is a polyfunctional radical, originating from a polyol R′(OH) x comprising x alcohol functional groups and x is an integer ranging from 2 to 6. The method according to the invention is particularly well suited to the synthesis of dialkylaminoalkyl (meth)acrylates from methyl (meth)acrylate and a dialkylaminoalcohol.
专利号:US-2002103381-A1 优先权日:2000-11-30 标 题 :Method for the synthesis of pyrazolines 发明人:BOLDI ARMEN M 摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.
专利号:US-9920160-B2 优先权日:2014-09-03 标题 :Method for synthesis of polymer containing multiple epoxy groups 发明人:GAO CHAO; ZHENG YAOCHEN; PENG LI; CAI SHENGYING; WENG ZHULIN 权利人:UNIV ZHEJIANG 摘要:A method for a synthesis of a polymer containing multiple epoxy groups includes steps of: under protection of nitrogen or argon, with a photosensitive free radical initiator under an ultraviolet light irradiation, initiating a mixture of a dithiol compound and alkynyl glycidyl ether or other alkynyl-containing compounds to proceed a thiol-yne polymerization, so as to obtain the polymer. The number of the epoxy groups is able to be adjusted through changing a type of a dithiol monomer, a mixing ratio of the dithiol monomer, and a mixing ratio between the alkynyl glycidyl ether and other alkynyl compounds. The present invention has advantages of: fast reaction, convenient process, easy post-processing, a large number of the epoxy groups, and adjustable and controllable content. The obtained polymer has a wide potential application in fields of coating, adhesive, ink, encapsulating material, resin for composite material, additive, high performance material, function material, and so on.
专利号:WO-2021233976-A1 优先权日:2020-05-19 标 题 :Process for the synthesis of isocyanate-free omega-hydroxy-urethanes, alpha-omega-diurethanes and oligo (poly)urethanes 发明人:NOCITO FRANCESCO; ARESTA MICHELE; DIBENEDETTO ANGELA 权利人:CONSORZIO INTERUNIVERSITARIO NAZ PER LA REATTIVITA CHIMICA E LA CATALISI; CATALISI INNOVATIVA PER IL RICICLO DEL CARBONIO E BIOPOLIMERI S R L 摘要:The synthesis of omega-hydroxyalkyl-urethanes, and of alfa-omega-diurethanes is reported which includes the reaction of diols with urea in presence of catalysts based on Ce at temperatures between 125 and 170°C over 4-8 h reaction time. A process for the production of oligomers of omega-hydroxyalkyl-urethanes is also reported based on the reaction of urea with diols in presence of Ce or Zr catalysts or Ce mixed oxides at 125-170°C over 4-20 h.
专利号:US-8450456-B2 优先权日:2007-12-21 标题:Activating peptide of the synthesis of aquaporins and cosmetic and/or pharmaceutical composition containing it 发明人:DAL FARRA CLAUDE; DOMLOGE NOUHA; BOTTO JEAN-MARIE 权利人:DAL FARRA CLAUDE; DOMLOGE NOUHA; BOTTO JEAN-MARIE; ISP INVESTMENTS INC 摘要:The present invention concerns a peptide of the general formula (I): n R 1 -(AA) n -X 1 —X 2 —X 3 -Pro-X 4 —X 5 —X 7 -(AA) p -R 2 , capable of activating the synthesis of proteins of the family of aquaporins. n The present invention also concerns a cosmetic, nutraceutical or pharmaceutical composition, comprising a peptide of general formula (I) as active principle. The invention also relates to the use of this new active principle in a cosmetic or nutraceutical composition, intended to improve the moisturizing and the barrier function of the epidermis and intended to stimulate cutaneous regeneration. The invention also relates to the use of this new active principle to realize a pharmaceutical composition, and in particular a dermatological composition, intended to regulate and/or stimulate the activity of the aquaporins and to thus treat the pathological dryness of the skin or mucosa. The invention also relates to a method of cosmetic treatment intended to prevent or combat against dryness of the skin and mucosa, and the manifestations of cutaneous ageing.
参考文献:10.1021/jp201137d 摘要:Shiraishi Y, Inoue T, Sumiya S, Hirai T. Entropy-driven thermal isomerization of spiropyran in viscous media. J Phys Chem A. 2011 Aug 25;115(33):9083–90. doi: 10.1021/jp201137d.