CAS: 114715-38-7; (S)-1-Benzyl-3-Aminopyrrolidine

相似化合物

114715-39-8 18471-40-4 103831-11-4

上下游产品

1-苄基-3-氨基吡咯烷 1-Benzyl-3-Aminopyrrolidine 18471-40-4
(3S)-3-Azido-1-(Phenylmethyl)Pyrrolidine 114636-29-2
1-苄基-3-吡咯烷酮 1-Benzyl-Pyrrolid-3-One 775-16-6
(S)-3-羟基-1-苄基吡咯烷 (S)-N-Benzyl-3-Hydroxypyrrolidine 101385-90-4
(R)-(+)-N-苄基-3-羟基吡咯烷 (R)-N-Benzyl-3-Hydroxypyrrolidine 101930-07-8
(3S)-3-氨基-1-苄基吡咯烷-2,5-二酮 (3S)-3-Amino-1-Benzylpyrrolidine-2,5-Dione 124223-92-3
(S)-(-)-1-苄基-3-(叔丁氧羰基氨基)吡咯烷 (S)-1-Benzyl-3-(Tert-Butoxycarbonylamino)Pyrrolidine 131852-53-4

(3S)-3-氨基-1-苄基吡咯烷-2,5-二酮置于sodium Tetrahydroborate,硫酸,盐酸体系中,用 四氢呋喃,水 用作溶剂,化学反应 6.5H,以99%的收率获得(S)-1-苄基-3-氨基吡咯烷
参考文献:Methods For Making Optically Active 3-Aminopyrrolidine-2,5-Dione Derivative And Optically Active 3-Aminopyrrolidine Derivative
标题:Methods For Making Optically Active 3-Aminopyrrolidine-2,5-Dione Derivative And Optically Active 3-Aminopyrrolidine Derivative
摘要:一种制备光学活性的3-氨基吡咯啉-2,5-二酮衍生物的方法,其化学式为(3),包括将光学活性的天冬氨酸酯衍生物,其化学式为(1)或(2),或其酸盐环化.一种制备光学活性的3-氨基吡咯啉衍生物的方法,其化学式为(9),包括还原光学活性的3-氨基吡咯啉-2,5-二酮衍生物,其化学式为(3).一种制备光学活性的3-氨基吡咯啉衍生物的方法,包括氢解光学活性的3-氨基吡咯啉衍生物,其化学式为(9).

专利信息

专利号:RU-2101279-C1
优先权日:1992-04-27
标 题 :Method of synthesis of derivatives of (s)-3-amino-1-benzylpyrrolidine, derivatives of (s)-aziridine as intermediate compounds for their synthesis and 1-benzyl-3-(s)-, 2-(s)-[(tert-butoxycarbonylamino)propionylamino]-pyrrolidine as an intermediate compound for quinolone-base antibacterial agents

专利号:US-8003785-B2
优先权日:2008-06-18
标 题 :Halo-substituted pyrimidodiazepines
发明人：CAI JIANPING; CHEN SHAOQING; CHU XIN-JIE; LUK KIN-CHUN; MISCHKE STEVEN GREGORY; SUN HONGMAO; WOVKULICH PETER MICHAEL
权利人:TAKEDA PHARMACEUTICAL
摘要:The present invention provides PLK1 inhibitor compounds of formula I: n nuseful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.

专利号:US-2008139805-A1
优先权日:2005-03-22
标题 :Process for producing carbapenem derivative having a 1-alkylpyrrolidine structure
发明人：MICHIDA MAKOTO; HAYASHI MASAKI; KOBAYASHI SATOSHI
权利人:DAIICHI SANKYO CO LTD
摘要:A process for the preparation of carbapenem-type antibacterial agents involving the following reaction: n n n n n n n n n n wherein R 1 is a C 1 -C 3 alkyl group, n is 0, 1 or 2, A is a C 1 -C 3 alkylene group, L is a leaving group, R 3 is a hydrogen atom, a C 1 -C 3 alkyl group or an amino protecting group, and the hydroxyl or carboxyl groups are optionally independently protected. In such process, amine compound (1) or a salt thereof acts as a synthetic intermediate. Such process is a less expensive and highly safe synthetic route for carbapenem-type antibacterial agents suitable for large-scale synthesis.

专利号:US-6613942-B1
优先权日:1997-07-01
标题 :Glucagon antagonists/inverse agonists
发明人：LING ANTHONY; GREGOR VLAD; GONZALEZ JAVIER; HONG YUFENG; KIEL DAN; KUKI ATSUO; SHI SHENGHUA; NAERUM LARS; MADSEN PETER; SAMS CHRISTIAN; LAU JESPER; PLEWE MICHAEL BRUNO; FENG JUN; TENG MIN; JOHNSON MICHAEL DAVID; TESTON KIMBERLY ANN; SIDELMANN ULLA GROVE; KNUDSEN LOTTE BJERRE
权利人:NOVO NORDISK AS
摘要:Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof are disclosed. The compounds act to antagonize the action of the glucagon peptide hormone.