CAS: 4891-29-6; 2-Neopentylthiophene

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2,2-dimethyl-1-(2-thienyl)-1-propanone pivaloyl chloride

合成工艺路线路线简述

    三甲基乙酰氯置于一水合肼,Tin(Ll) Chloride体系中,用 乙醇,二氯甲烷 作为反应溶剂,化学反应 141.0H,反应生成 2-新戊基噻吩
    参考文献:Jp5776099
    标题:Jp5776099

    专利信息


    专利号:US-2008086013-A1
    优先权日:2006-06-15
    标 题:Carbometallation of alkynes and improved synthesis of uniquinones
    发明人:LIPSHUTZ BRUCE H
    权利人:UNIV CALIFORNIA
    摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

    专利号:US-11629162-B2
    优先权日:2015-12-17
    标 题:Triterpene saponin variants, methods of synthesis and use thereof
    发明人:TAN DEREK S; GIN DAVID Y; WALKOWICZ WILLIAM E; FERNANDEZ-TEJADA ALBERTO; RAGUPATHI GOVINDASWAMI
    权利人:MEMORIAL SLOAN KETTERING CANCER CENTER
    摘要:A number of triterpene saponin variants with different modifications on their central glycosyl ester linkage are described. Also described are methods of making and method of using such triterpene saponin variants.

    专利号:US-2019127396-A1
    优先权日:2017-11-01
    标题 :Synthesis of boronate ester derivatives and uses thereof

    专利号:US-2020308197-A1
    优先权日:2017-11-01
    标 题 :Synthesis of boronate ester derivatives and uses thereof

    专利号:US-10458995-B2
    优先权日:2016-03-25
    标 题 :Combinatorial synthesis and biomarker development
    发明人:MOOLA MURALIDHAR REDDY
    权利人:MOOLA MURALIDHAR REDDY
    摘要:Provided herein are methods, kits, and compositions for use in the diagnosis and treatment of diseases. Peptoids recognized by Alzheimers disease specific antibodies are identified.

    专利号:US-6995142-B2
    优先权日:1998-04-30
    标题 :Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    发明人:DRAGOVICH PETER SCOTT; WEBBER STEPHEN EVAN; PRINS THOMAS JAY; ZHOU RU; MARAKOVITS JOSEPH TIMOTHY; JOHNSON JR THEODORE O
    权利人:AGOURON PHARMA
    摘要:Peptido and peptidomimetic compounds of the formula: n nwherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
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    合成参考文献


    摘要:Amatore, M.; Aubert, C.; Malacria, M.; Petit, M., Science of Synthesis Knowledge Updates, (2012) 3, 57.
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