专利号:WO-2022229983-A1 优先权日:2021-04-29 标题:Sugar esters and sugar alcohol esters of short chain fatty acids and compositions thereof 发明人:KANUMURU RAHUL RAJU; SHAJI GEORGE KOCHUMALAYIL; ANINDYA SIL; SURANENI RAVIKUMAR; GARUDADRI LAKSHMI PRASANNA KUMAR 权利人:FERTIS INDIA PVT LTD 摘要:The present invention discloses compositions comprising sugar esters and sugar alcohol esters of short chain fatty acids and their use in pest management. These compositions possess antiviral, antimicrobial, insecticidal, pesticidal and herbicidal properties and their potential use in controlling, Lepidoptera, Hemiptera and Thysanoptera insects, Tomato spotted wilt viruses, Tobacco mosaic viruses. The present invention also dicloses compositions of sugar esters and sugar alcohol esters of short chain fatty acids as potential agents for treating oral and dermatological problems of microbial origin. The present invention further discloses the synthesis of novel sugar esters and sugar alcohol esters of short chain fatty acids.
专利号:WO-2025133718-A1 优先权日:2023-12-22 标题 :An efficient process for the synthesis of paraxanthine 发明人:KANUMURU RAHUL RAJU; KOCHUMALAYIL SHAJI GEORGE; SURANENI RAVIKUMAR; VANA MURALI MOHANARAO 权利人:FERTIS INDIA PVT LTD 摘要:The processes disclosed are simple, economical for large scale industrial production resulting in high purity and quality of paraxanthine. Further the process produces high-purity paraxanthine suitable for various applications in the nutraceutical, pharmaceutical, and cosmetic industries.
专利号:WO-2024121871-A1 优先权日:2022-12-09 标 题 :Genetic modification of microbes for production of nitrogen and carbon-containing compounds 发明人:KANUMURU RAHUL RAJU 权利人:FERTIS INDIA PVT LTD 摘要:The present invention relates to a novel method for sustainable in vitro and in vivo production of nitrogen and carbon containing compounds such as and not limited to Proteins, Enzymes, peptides amino acids, nucleotides, vitamins, etc. The present invention relates to a novel method that includes gene modifications in microbes, more specifically involving gene modifications resulting in nitrogen fixation and/or ammonia fixation or increased nitrogen fixation and/or ammonia fixation or carbon fixation/increased carbon fixation or Hydrogen fixation/increased Hydrogen fixation with increased synthesis/ regeneration of anyone or all compounds including ATP, NADH, NADPH, Pyruvate and Acetyl CoA with or without utilisation/reduction enhanced utilisation/reduction of Nitrate, Nitrite, N2O, N2O2 and/or carbon containing substrates
专利号:US-2023271983-A1 优先权日:2020-07-29 标题 :Functionalized isonitriles and products, preparation and uses thereof 发明人:SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA 权利人:UNIV SANTIAGO COMPOSTELA 摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.
专利号:US-6930227-B1 优先权日:1999-05-26 标题:Camellia sinensis gene encoding a caffeine synthesis associated n-methyl transferase with 7-methylxanthine n3 methyl transferase, theobromine n1 methyl transferase, and paraxanthine n3 methyl transferase activities and use thereof 发明人:MIZUNO MISAKO; ASHIHARA HIROSHI; MIZUNO KOUICHI; FUJIMURA TATSUHITO 权利人:MITSUI CHEMICALS INC 摘要:The present invention makes it possible to efficiently produce an N-methyl transferase with 7-methylxanthine N3 methyl transferase, theobromine N1 methyl transferase, and paraxanthine N3 methyl transferase activities that can be utilized as an industrial, food, or medical enzyme. In addition, the present invention makes it possible to modify the caffeine biosynthesis metabolism of caffeine producing plants, plant tissues, or plant cells, thereby efficiently producing caffeine metabolism based compounds or modifying the production of caffeine in the plants.
专利号:CN-108753740-A 优先权日:2018-06-25 标 题 :Enzyme composition for catalyzing the synthesis of theobromine and its application in biological preparation of theobromine
1: Szlapinski SK, Charrette A, Guthrie N, Hilmas CJ. Paraxanthine safety and comparison to caffeine. Front Toxicol. 2023 Feb 2;5:1117729. doi: 10.3389/ftox.2023.1117729. 2: Jäger R, Purpura M, Wells SD, Liao K, Godavarthi A. Paraxanthine Supplementation Increases Muscle Mass, Strength, and Endurance in Mice. Nutrients. 2022 Feb 20;14(4):893. doi: 10.3390/nu14040893. 3: Purkiewicz A, Pietrzak-Fiećko R, Sörgel F, Kinzig M. Caffeine, Paraxanthine, Theophylline, and Theobromine Content in Human Milk. Nutrients. 2022 May 25;14(11):2196. doi: 10.3390/nu14112196.
合成参考文献
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