CAS: 775-64-4; 2-Adamantan-1-Yl-Propan-2-Ol

相似化合物

702-98-7 14648-57-8 26750-08-3

上下游产品

CAS号57680-77-0 1-adamantylmagn... | CAS号67-64-1 丙酮 | CAS号773-33-1 1-ISOPROPENYLAD... | CAS号1148-11-4 N-CBZ-L-脯氨酸 | CAS号917-54-4 甲基锂 | CAS号2094-72-6 1-金刚烷甲酰氯 | CAS号1660-04-4 1-金刚烷甲酮 | CAS号917-64-6 甲基碘化镁 | CAS号2094-73-7 金刚烷-1-甲酸乙酯 | CAS号768-90-1 1-溴金刚烷 | CAS号880-49-9 3-isopropyl-1-a... | CAS号1660-04-4 1-金刚烷甲酮 | CAS号120626-27-9 1-nitro-2-(1-ad... | CAS号773-32-0 1-ISOPROPYLADAM... | CAS号773-33-1 1-ISOPROPENYLAD... | CAS号68388-88-5 2-(1-金刚烷)-2-丙基碳酸苯酯

1-溴金刚烷置于magnesium,1,2-二溴乙烷体系中,用 乙醚 作为反应溶剂,化学反应 15.25H,反应生成 2-(1-金刚烷基)-2-丙醇
参考文献:Yurchenko,A. G.; Fedorenko,T. V.,Journal Of Organic Chemistry Ussr (English Translation),1987,Vol. 23,# 5,P. 875-880
标题:Yurchenko,A. G.; Fedorenko,T. V.,Journal Of Organic Chemistry Ussr (English Translation),1987,Vol. 23,# 5,P. 875-880

专利信息

专利号:US-11161869-B2
优先权日:2017-04-12
标 题:Thermally-cleavable protecting and linker groups
发明人：CROSBY STUART RICHARD; JENNISON MATHEW; BRENNAN JOSEPH
权利人:EVONETIX LTD
摘要:The present invention relates to chemical linkers and protecting groups, compounds and compositions containing the chemical linkers or protecting groups, and intermediates and processes that can be used to prepare them. The chemical linkers and protecting groups are based on pyrrolidine and piperidine activating groups, which undergo intramolecular cyclisation upon heating with release of carbon dioxide, thereby releasing the organic compound from a substrate. In particular, those chemical linkers and protecting groups are useful in the solid phase synthesis of oligonucleotides according to the following representative schemes.