CAS: 2968-93-6; 2-(4-(Trifluoromethyl)Phenyl)Ethanol

上下游产品

CAS号32857-62-8 4-(三氟甲基)苯乙酸 | CAS号135325-18-7 2-(4-(三氟甲基)苯基)乙酸甲酯 | CAS号30934-62-4 4-三氟甲基苯乙醛 | CAS号130365-87-6 4-(三氟甲基)苯乙基溴 | CAS号402-50-6 4-(三氟甲基)苯乙烯 | CAS号41360-55-8 2-[4-(三氟甲基)苯基]乙酰胺 | CAS号402-45-9 4-(三氟甲基)苯酚 | CAS号107-21-1 乙二醇 | CAS号75-21-8 环氧乙烷 | CAS号26416-26-2 4-methylbenzene... | CAS号30934-62-4 4-三氟甲基苯乙醛 | CAS号130365-87-6 4-(三氟甲基)苯乙基溴 | CAS号178685-14-8 1-(2-iodoethyl)...

4-(三氟甲基)苄醇置于锂硼氢,戴斯-马丁氧化剂,Sodium Hydroxide体系中,用 异丙醇 用作溶剂,化学反应生成4-(三氟甲基)苯乙醇
参考文献:伯醇的单碳认证和涉及 Jocic 型反应的醛的还原认证
标题:伯醇的单碳认证和涉及 Jocic 型反应的醛的还原认证
摘要:(三氯甲基)甲醇在一次操作中由醇或醛形成,可在涉及 Libh4 的 Jocic 型反应中转化为伯醇.最终结果是方便的两步,伯醇的单碳同源或醛的还原性单碳同源,具有广泛的底物范围.该方法是步骤经济的,它很好地补充了已建立的单碳同源策略.
Doi:10.1002/ejoc.201501089

专利信息

专利号:US-11161827-B2
优先权日:2019-04-05
标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
发明人：Zhang xiao-xiang; Lang kai
权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-2020317627-A1
优先权日:2019-04-05
标 题:Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical c-h amination

专利号:US-2005240034-A1
优先权日:2002-05-07
标 题 :Artemisinin-based peroxide compounds as broad spectrum anti-infective agents
发明人：AVERY MITCHELL; MURALEEDHARAN KANNOTH M
权利人:AVERY MITCHELL; MURALEEDHARAN KANNOTH M
摘要:Described herein is the synthesis, bioassay results and utility of new C- 9 and C- 10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.