CAS: 3430-16-8; 3-Bromo-5-Methylpyridine

相似化合物

142337-95-9 866683-52-5 145743-85-7

上下游产品

CAS号625-92-3 3,5-二溴吡啶 | CAS号823-96-1 三甲基环三硼氧烷 | CAS号591-22-0 3,5-二甲基吡啶 | CAS号10477-94-8 3-甲基-5-苯基吡啶 | CAS号3430-19-1 3-氨基-5-甲基吡啶 | CAS号30413-53-7 3-乙炔基-5-甲基吡啶 | CAS号20826-04-4 5-溴烟酸 | CAS号173999-18-3 5-甲基吡啶-3-硼酸 | CAS号1721-12-6 1-(2-甲基吡啶-3-基)乙酮 | CAS号42972-46-3 1-(5-甲基吡啶-3-基)乙酮

3,5-二甲基吡啶置于n-溴代丁二酰亚胺(Nbs),偶氮二异丁腈体系中,用 四氯化碳 用作溶剂,化学反应 2.0H,反应生成3-溴-5-甲基吡啶
参考文献:Wo2007/107758
标题:Wo2007/107758

专利信息

专利号:US-7626045-B2
优先权日:2005-01-14
标题:Synthesis of himbacine analogs
发明人：THIRUVENGADAM TIRUVETTIPURAM K; WANG TAO; LIAO JING; CHIU JOHN S; TSAI DAVID J S; LEE HONG-CHANG; WU WENXUE; FU XIAOYONG
权利人:SCHERING CORP
摘要:The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer. n An example of a step in the synthesis of such a himbacine analog is as follows:

专利号:US-2018051042-A1
优先权日:2016-08-22
标题 :Methods for forming saturated (hetero)cyclic borylated hydrocarbons and related compounds
发明人：SMITH III MILTON R; SHANNON TIMOTHY M; MALECZKA JR ROBERT E; FORNWALD RYAN M
权利人:UNIV MICHIGAN STATE
摘要:The disclosure relates to methods for forming at least partially saturated cyclic and heterocyclic borylated hydrocarbons, as well as related compounds, which can be precursor compounds in the synthesis of any of a variety of pharmaceutical or medicinal compounds with a desired structure and/or stereochemistry for drug synthesis or drug candidate evaluation. The methods generally include reduction of an unsaturated cyclic or heterocyclic borylated hydrocarbon having a boron-containing substituent at an sp 2 -carbon, where such reduction converts the sp 2 -carbon to an sp 3 -carbon at the point of attachment of the boron-containing substituent. The methods can exhibit a selectivity for syn-addition during reduction, which can provide stereospecific products, such as when the unsaturated cyclic or heterocyclic reactant is multiply substituted with boron groups and/or other functional groups.

专利号:US-2006173189-A1
优先权日:2005-01-14
标题 :Synthesis of himbacine analogs

专利号:US-2007099919-A1
优先权日:2005-10-06
标题 :Composition and synthesis of new reagents for inhibition of HIV replication

专利号:US-2009203925-A1
优先权日:2005-01-14
标 题 :Synthesis of himbacine analogs

专利号:CA-2594741-A1
优先权日:2005-01-14
标题 :Synthesis of himbacine analogs