CAS: 458-35-5; 4-(3-Hydroxyprop-1-En-1-yl)-2-Methoxyphenol

该化合物是一种自然产生的有机化合物,被归类为单硅醇,是离心生物合成的主要前体.它具有一种含有丙烯基副链的苯球结构,有助于其在氧化性联结反应中的回活动.该化合物因其在植物细胞壁形成中的作用以及作为融合离心聚合物和其他苯基聚合物的中间体而得到广泛研究.它的高度纯度和定义明确的化学特性使得它对于生物化学,植物生理学和材料科学的研究具有价值. 康菲里醇还被用于酶和化学研究,以调查离心聚合物途径,为可持续生物材料开发提供见解.

结构式图片

上下游产品

3-(4-hydroxy-3-methoxyphenyl)acrylic acid (E,E)-3-(4-hydroxy-3-methoxyphenyl)allyl 3-(4-hydroxy-3-methoxyphenyl)acrylate ethyl ferulate coniferaldehyde3,4-Dihydroxybenzoic acid 3-Guaiacylpropanol (E)-4-(3-methoxy-1-propenyl)-2-methoxyphenol vanillin

合成工艺路线路线简述

    丁香酚置于eugenol Oxidase From Rhodococcus Jostii Rha1体系中,用 二甲基亚砜 作为反应溶剂,化学反应 4.0H,反应生成 松柏醇
    参考文献:何氏红球菌rha1丁香酚氧化酶的生物催化性质和结构分析:多功能氧化生物催化剂.
    标题:何氏红球菌rha1丁香酚氧化酶的生物催化性质和结构分析:多功能氧化生物催化剂.
    摘要:氧化酶的选择性:约氏红球菌(rhodococcus Jostii) Rha1的丁香酚氧化酶是一种强大的生物催化剂,可用于多种氧化反应,包括脱氢反应以及消旋外消旋仲醇的动力学拆分.晶体结构提供了对这种氧化生物催化剂的选择性的了解.
    DOI:10.1002/cbic.201600148

    海关参考信息

    专利信息


    专利号:US-7872160-B2
    优先权日:2008-03-31
    标题:Single pot process for the regioselective synthesis of neolignan framework asarones
    发明人:UPPULURI VENKATA MALLAVADHANI; AKELLA VENKATA SUBRAHMANYA SUDHAKAR; MAHAPATRA ANITA
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention provides a single pot process for the regioselective synthesis of neolignan framework [3(R)-Ethyl-2(S)-methyl-3-(2″,4″,5″-trimethoxyphenyl)-1-(2′,4′,5′-trimethoxyphenyl)propane from toxic β-isomer rich asarone using montmorillonite acidic clay by employing microwave organic reaction enhancement (MORE) chemistry. This may be useful as versatile synthetic protocol for the synthesis of a large number of lignan and neolignan frameworks.

    专利号:WO-2023204823-A1
    优先权日:2022-04-23
    标题 :Process for synthesis of lignocellulosic based bioproducts
    发明人:JAIN ARPAN
    权利人:JAIN ARPAN
    摘要:The present invention relates to a process for the synthesis of lignocellulosic-based bioproducts. The process involves the biochemical conversion of lignocellulosic biomass generated through agriculture, non-agriculture, and forest that produces streams of high-value goods including cosmetic ingredients, nutraceuticals, carbon fiber, activated carbon, graphene, low-calorie sugar, bioplastic, cellulose pulp, and nano-cellulose based aerogel. The process comprises; a process stage-1 for removing the phenolic compounds (lignin) from lignocellulosic biomass as well as decreasing the crystallinity of the cellulose using alkaline modified ethyl-hydro-oxides (m-EHOs) extraction, a process stage-2 for removal of the hemicellulose fraction of the holocellulose using mild sulfuric acid extraction, and a process stage-3 for chemically treating cellulose pulp with alkaline modified ethyl-hydro-oxides (m-EHOs) solvent for the production of nano-cellulose and micro-cellulose fractions. Along with the production of high-value goods, the process generates energy.

    专利号:US-10604479-B2
    优先权日:2013-11-18
    标 题:Continuous process for the one-pot synthesis of metal salts and metal complexes
    发明人:LEONARDI GIULIANO; GASPERONI GIOVANNI
    权利人:VOLARE & CONNECTING LLC; LEONARDI GIULIANO; NOVUS INT INC
    摘要:A continuous process is described for the one-pot synthesis of compounds, such as metal salts and metal complexes, as well as optionally for the protection of the compounds thus obtained by coating and/or impregnation with suitable compounds.

    专利号:US-9809522-B2
    优先权日:2015-09-11
    标 题 :Selective liquefaction of lignin and biomass in a mixture of sub- and supercritical fluids in absence or presence of heterogeneous catalysts
    发明人:SMIRNOVA ALEVTINA; LYNDE CHRIS; Numan-Al-Mobin Abu Md; RAJAPPAGOWDA RUDRESH BOMMADIHALLI
    权利人:SOUTH DAKOTA BOARD OF REGENTS
    摘要:Disclosed herein are methods for selective synthesis of specific phenolic products by means biomass or biomass products liquefaction, manipulation of the said selectivity in favor of one specific phenolic compound or a mixture of specific phenolic compounds, and the synthesis of the phenolic compounds from a liquid or biomass organic fraction produced in presence of a homogeneous catalyst in supercritical state or a mixture of said homogeneous and one or several heterogeneous catalysts mixed with water in sub-critical, near-critical, or supercritical condition.

    专利号:US-11384367-B2
    优先权日:2016-12-22
    标题:Synthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms
    发明人:GLADDEN JOHN M; SKERKER JEFFREY M; KEASLING JAY D; KIRBY JAMES; YAEGASHI JUNKO
    权利人:UNIV CALIFORNIA; NAT TECH & ENG SOLUTIONS SANDIA LLC; BATTELLE MEMORIAL INSTITUTE FOR MANAGEMENT AND OPERATION OF PACIFIC NORTHWEST NAT LABORATORY; NATIONAL TECH AND ENGINEERING SOLUTIONS OF SANDIA LLC
    摘要:The present invention provides for a method of converting a depolymerized lignin aromatic compound into a bioproduct, comprising: (a) providing a composition comprising a depolymerized lignin aromatic compound, optionally a depolymerized cellulose, and optionally a depolymerized hemicellulose, and (b) introducing a genetically modified microorganism to the composition, wherein the genetically modified microorganism is capable of converting the depolymerized lignin aromatic compound into a bioproduct; such that the depolymerized lignin aromatic compound is converted into a bioproduct.

    专利号:US-6066780-A
    优先权日:1991-04-26
    标题 :Modification of lignin synthesis in plants
    发明人:BOUDET ALAIN MICHEL; INZE DIRK GUSTAAF; SCHUCH WOLFGANG WALTER
    权利人:ZENECA LTD
    摘要:The synthesis of lignin by plants is controlled by transformation of the plant genome with a recombinant gene construct which contains the gene specifying an enzyme critical to the synthesis of a lignin precursor, which gene may be in antisense orientation so that it is transcribed to mRNA having a sequence complementary to the equivalent mRNA transcribed from the endogenous gene thus leading to suppression of lignin synthesis. If the recombinant gene has the lignin enzyme gene in normal, or 'sense' orientation, increased production of the enzyme may occur when the insert is the full length DNA but suppression may occur it only a partial sequence is employed.
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    合成参考文献


    参考文献:10.1371/journal.pone.0021784
    摘要:Saha R, Suthers PF, Maranas CD. Zea mays iRS1563: A Comprehensive Genome-Scale Metabolic Reconstruction of Maize Metabolism. PLoS ONE. 2011 Jul 06;6(7):e21784. doi: 10.1371/journal.pone.0021784.
    参考文献:10.1021/jp204367k
    摘要:Dean JC, Buchanan EG, James WH, Gutberlet A, Biswas B, Ramachandran PV, Zwier TS. Conformation-specific spectroscopy and populations of diastereomers of a model monolignol derivative: chiral effects in a triol chain. J Phys Chem A. 2011 Aug 04;115(30):8464–78. doi: 10.1021/jp204367k.
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