CAS: 489-35-0; Gossypetin

该化合物是主要在棉花植物(戈斯比亚物种)和其他植物中发现的氟氯素化合物,其特点是黄色素,以其抗氧化性特性而著称,有助于其潜在的健康利益;高斯卫平因展示了一种氟芳结构,其特点是一种铬脊椎,其氢氧基体在极地溶剂中的再活性和溶性得到加强;该化合物因其防炎,抗微生物和抗癌症活动而引起对药理研究的兴趣.此外,高斯比安平因可能在防治病原和环境压力的植物防护机制中发挥作用,它存在于饮食来源中,表明它有可能对人类健康产生影响,尽管需要进一步研究以充分阐明其生物影响和行动机制.

结构式图片

上下游产品

2-(3,4-dimethoxy-phenyl)-3-hydroxy-5,7,8-trimethoxy-chromen-4-one 5,7,3',4'-tetrahydroxy-3,8-dimethoxyflavone quercetol 2sin°Crassoside D22-(3,4-dimethoxy-phenyl)-5-hydroxy-3,7,8-trimethoxy-chromen-4-one 3,5,7,8-tetraacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one hexa-O-methylogossypetin 3,5-dihydroxyphenol

合成工艺路线路线简述

    Gossypetin-3,8-Dimethyl Ether 5-O-β-D-Glucopyranoside置于acetate Buffer,氢碘酸,β-Glucosidase,苯酚体系中,化学反应 24.5H,反应生成 棉花素
    参考文献:Polyoxygenated Flavonoids From Eugenia Edulis
    标题:Polyoxygenated Flavonoids From Eugenia Edulis
    摘要:Leaves Of Eugenia Edulis Contain The New Polyoxygenated Flavonoid Derivatives,Gossypetin-3,8-Dimethyl Ether-5-O-Beta-Glucoside; Gossypetin-3,5-Dimethyl Ether,And Myricetin-3,5,3'-Trimethyl Ether. In Addition,Ten Known Polyphenolics Were Also Isolated And Identified. All Structures Were Established On The Basis Of Chemical And Spectral Evidence,Including Esi-Ms And C-13 NMR. (C) 2003 Elsevier Ltd. All Rights Reserved.
    DOI:10.1016/s0031-9422(03)00437-0

    海关参考信息

    专利信息


    专利号:US-2025257331-A1
    优先权日:2024-02-09
    标题 :FLAVONOID GLYCOSIDE GLYCOSYLTRANSFERASE LbUGT71BX1 IN LAPORTEA BULBIFERA AS WELL AS THE CODING GENE AND THE USE THEREOF
    发明人:WU LAN; XIANG LI; GAO RANRAN; CHEN SHILIN; SHI YUHUA; YIN QINGGANG; WANG MENGYUE; CHU YANG; WANG WENTING
    权利人:INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS
    摘要:The invention discloses a flavonoid glycoside glycosyltransferase LbUGT71BX1 in laportea bulbifera as well as the coding gene and the use thereof. The amino acid sequence of the flavonoid glycoside glycosyltransferase LbUGT71BX1 is shown as SEQ ID NO: 2. The nucleotide sequence of the coding gene of the flavonoid glycoside glycosyltransferase LbUGT71BX1 is shown as SEQ ID NO: 1. According to the invention, on the basis of relevant results of the second-generation transcriptome and the third-generation full-length transcriptome sequencing of the laportea bulbifera , the last-step key enzyme LbUGT71BX1 for the synthesis of the flavonoid glycoside in the laportea bulbifera is screened and identified by using a reverse genetics method, filling the terminal blank of the biosynthesis pathway of the flavonoid glycoside in the laportea bulbifera.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-12036300-B2
    优先权日:2021-03-31
    标题:Methods and compositions for improving skin
    发明人:LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
    权利人:OREAL
    摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.

    专利号:CN-116829544-A
    优先权日:2020-12-10
    标题 :Synthesis method of flavonoid dimers and oligomers and application thereof
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    成立日期:2023-3-17登记机关:武汉市江夏区市场监督管理局
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    CAS号:489-35-0
    中文名:棉花素
    英文名:GOSSYPETIN
    纯度:99% HPLC1G/5G/1KG
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    主要参考文献


    1: Ali Khan MS, Ahmed N, Misbah, Arifuddin M, Zakaria ZA, Al-Sanea MM, Khundmiri SUK, Ahmed I, Ahmed S, Mok PL. Anti-nociceptive mechanisms of flavonoids-rich methanolic leaf extract from Terminalia coriacea (Roxb.) Wight & Arn. leaves. Food Chem Toxicol. 2018 Mar 17. pii: S0278-6915(18)30170-4. doi: 10.1016/j.fct.2018.03.021. [Epub ahead of print] doi: 10.1080/09168451.2017.1412246. Epub 2018 Jan 3. doi: 10.4268/cjcmm20162424. Chinese. doi: 10.4103/0974-8490.210326.
    5: Lee MS, Tsai CW, Wang CP, Chen JH, Lin HH. Anti-prostate cancer potential of gossypetin via inducing apoptotic and autophagic cell death. Mol Carcinog. 2017 Dec;56(12):2578-2592. doi: 10.1002/mc.22702. Epub 2017 Aug 3. doi: 10.1016/j.jep.2017.02.046. Epub 2017 Apr 10. doi: 10.1002/bmc.3795. Epub 2016 Aug 12. pii: E28. doi: 10.3390/plants5020028.
    9: Raj U, Varadwaj PK. Flavonoids as Multi-target Inhibitors for Proteins Associated with Ebola Virus: In Silico Discovery Using Virtual Screening and Molecular Docking Studies. Interdiscip Sci. 2016 Jun;8(2):132-41. doi: 10.1007/s12539-015-0109-8. Epub 2015 Aug 19. Erratum in: Interdiscip Sci. 2016 Jun;8(2):142. doi: 10.3109/10715762.2015.1053878. Epub 2015 Aug 14. doi: 10.1186/s12990-015-0011-8.

    合成参考文献


    参考文献:10.1007/bf03190570
    摘要:Kolawole JA, Maduenyi A. Effect of zobo drink (Hibiscus sabdariffa water extract) on the pharmacokinetics of acetaminophen in human volunteers. European Journal of Drug Metabolism and Pharmacokinetics. 2004 Mar;29(1):25–9. doi: 10.1007/bf03190570.
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