CAS: 5957-80-2; (4Ar,9S,10As)-5,6-Dihydroxy-7-Isopropyl-1,1-Dimethyl-2,3,4,9,10,10A-Hexahydro-1H-9,4A-(Epoxymethano)Phenanthren-12-One

上下游产品

CAS号3650-09-7 鼠尾草酸 | CAS号80225-53-2 迷迭香酚

鼠尾草酸置于silver(L) Oxide体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.5H,以67%的收率获得产物鼠尾草苦内脂
参考文献:迷迭香中的鼠尾草酸和鼠尾草酚(抗氧化剂)由沙瓦拉(sawara)的主要成分哌啶酸合成.
标题:迷迭香中的鼠尾草酸和鼠尾草酚(抗氧化剂)由沙瓦拉(sawara)的主要成分哌啶酸合成.
摘要:鼠尾草酸(2)是迷迭香(rosmarinus Officinalis)中的一种主要抗氧化剂,它是由sawara(chamaecyparis Pisifera)的主要成分pisiferic Acid(1)合成的,其中苯酚使用间氯过氧化苯甲酸酯进行邻位氧化. Mcbpo),氯乙酰基间氯过氧化苯甲酰(camcbpo)或2-碘氧基苯甲酸(ibx).鼠尾草酚(3)是迷迭香中的另一种抗氧化剂,是由鼠尾草酸通过氧化银氧化而合成的.据报道,其对痤疮丙酸杆菌(atcc 6919)(最小抑菌浓度(mic)杯/毫升)和金黄色葡萄球菌me / Gm / Tc耐药(atcc 33592)(mic杯/毫升)的肌酸和鼠尾草酚均具有有效的抗菌活性.
DOI:10.1248/cpb.58.27

专利信息

专利号:US-6391344-B2
优先权日:1999-12-02
标题:Method of promoting synthesis of nerve growth factor
发明人：KOSAKA KUNIO; MIYAZAKI TOSHITSUGU; ITO HISATOMI
权利人:NAGASE & CO LTD
摘要:A method of promoting the synthesis of nerve growth factor comprising administering an effective amount of rosemary and/or sage extracts or carnosic acid and/or carnosol as an effective ingredient to a subject requiring such promotion. The present method can safely and efficiently promote the production of NGF in the living body, without being accompanied by a side effect such as a loss of a quantitative balance of hormones in the living body.

专利号:WO-2017046598-A1
优先权日:2015-09-16
标题:Treatment of acute inflammatory disorders
发明人：CRISANTI ANDREA; CANAVESE MIRIAM
权利人:CRISANTI ANDREA; IMP INNOVATIONS LTD
摘要:The present invention relates to a VEGF receptor agonist for use in the treatment of an acute inflammatory disorder associated with the overproduction of pro-inflammatory cytokine, administered with an agent that induces the synthesis of Nrf2. The invention also relates to pharmaceutical combinations comprising a VEGF receptor agonist and an agent that induces the synthesis of Nrf2, and kits comprising these agents. The described uses, combinations and methods may prevent or reduce the dis-regulated activation of an inflammatory response and reduce endothelial damage.

专利号:US-2014357576-A1
优先权日:2013-05-31
标题:Methods for enhancement of muscle protein synthesis
发明人：BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
权利人:NESTEC SA
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

专利号:US-11273138-B2
优先权日:2017-11-02
标 题 :Use of amino acid supplementation for improved muscle protein synthesis
发明人：WOLFE ROBERT R; FERRANDO ARNY
权利人:BIOVENTURES LLC
摘要:The present invention encompasses an amino acid composition for stimulating muscle protein synthesis. Further, the present disclosure relates generally to the use of an anabolic amino acid composition for the stimulation of muscle protein synthesis. In particular, disclosed are compositions and methods of using the same for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal, especially an adult mammal. Also provided are kits comprising a composition for the stimulation of muscle protein synthesis and, in certain embodiments, instructions for administration.

专利号:WO-2015040533-A1
优先权日:2013-09-19
标题:Methods for enhancing muscle protein synthesis during energy deficit
发明人：BAILEY DAVID MARK; ZALTAS ERIC SCOTT; STELLINGWERFF TRENT; MOORE DANIEL RYAN; HAWLEY JOHN ALAN; BURKE LOUISE MARY
权利人:PREMIER NUTRITION CORP
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis during periods of negative energy balance, or energy deficit. The methods include administering to an individual suffering from energy deficit a composition comprising protein in an amount from about 15 g to about 30 g during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof. The methods also include administering to an individual suffering from energy deficit a composition comprising protein during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof, wherein the protein is administered in a dose that is higher than doses typically recommended for individuals experiencing energy balance.

专利号:US-2014294788-A1
优先权日:2013-03-26
标 题 :Methods for enhancing muscle protein synthesis following concurrent training
发明人：BAILEY DAVID MARK; ZALTAS ERIC SCOTT; MOORE DANIEL RYAN; STELLINGWERFF TRENT
权利人:NESTEC SA
摘要:The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.