CAS: 127972-02-5; (5-Formyl-2-Methoxyphenyl)Boronic Acid

主要参考文献

参考标题:Ring Strain And Total Syntheses Of Modified Macrocycles Of The Isoplagiochin Type
作者:Andreas Speicher,Timo Backes,Kerstin Hesidens,Jürgen Kolz
摘要:Macrocycles Of The Bisbibenzyl-Type Are Natural Products That Are Found Exclusively In Bryophytes (Liverworts). The Molecular Framework Of The Subtype "Isoplagiochin" Is Of Substantial Structural Interest Because Of The Chirality Of The Entire Molecule, Which Arises From Two Biaryl Axes In Combination With Two Helical Two-Carbon Units In A Cyclic Arrangement. From A Structural As Well As A Synthetic Point Of View We Report On The Total Synthesis Of Compounds Which Possess More Rigid Two-Carbon Biaryl Bridges Like Stilbene (E Or Z) Or Even Tolane Moieties Which Were Introduced Starting With A Sonogashira Protocol. The Mcmurry Method Proved To Be A Powerful Tool For The Cyclization To These Considerably Ring-Strained Macrocycles.

合成参考文献

参考文献:10.3851/imp1632
摘要:Trippier PC, McGuigan C, Balzarini J. Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: monophenylboronic acids. Antivir Chem Chemother. 2010 Aug 11;20(6):249–57. doi: 10.3851/imp1632.