CAS: 146328-85-0; 5-Bromo-2-Fluorobenzoic Acid

相似化合物

179897-89-3 93777-26-5 57381-59-6

上下游产品

CAS号93777-26-5 5-溴-2-氟苯甲醛 | CAS号124-38-9 二氧化碳 | CAS号460-00-4 对氟溴苯 | CAS号445-29-4 邻氟苯甲酸 | CAS号146328-84-9 2-氟-5-苯基苯甲酸 | CAS号214210-17-0 5-溴-2-氟苯甲酰胺 | CAS号198477-89-3 1-(5-溴-2-氟苯基)乙酮 | CAS号57381-59-6 5-溴-2-氟苯甲酸甲酯 | CAS号56341-31-2 2-溴-9h-占吨醇-9-酮 | CAS号773140-42-4 5-溴-2-氟苯甲酰氯 | CAS号949443-48-5 N-苯基-2-溴-5-氟苯甲酰胺 | CAS号612835-53-7 5-溴-2-氟苯甲酸乙酯

邻氟苯甲酸置于sodium Bromate,硫酸体系中,用 水 用作溶剂,化学反应 1.0H,以88%的收率获得5-溴-2-氟苯甲酸
参考文献:新型铁膦恶唑啉配合物的合成与结构表征
标题:新型铁膦恶唑啉配合物的合成与结构表征
摘要:合成了铁的第一膦氧恶唑啉螯合物,并研究了它们的结构和电子性质.
Doi:10.1016/j.Jorganchem.2008.06.031

专利信息

专利号:WO-2024159285-A1
优先权日:2023-01-30
标题 :Nav1.7- and/or nav1.8-inhibiting aryl pyridine compounds, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人：BARREIRO GABRIELA; SANT’ANA DANILO PEREIRA DE; MONTEIRO JÚLIA LAMMOGLIA; GAMBA LUIS EDUARDO REINA; LIMA LÃ?DIA MOREIRA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO – UFRJ
摘要:The present invention relates to Nav1.7- and/or Nav1.8-inhibiting aryl pyridine compounds. More specifically, the present invention relates to aryl pyridines comprising formula (I): (I), in which the substituents R1 to R10 are selected independently of the groups defined in the description, as well as to processes for preparing same, compositions comprising at least one of these compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits. The present invention pertains to the fields of medicinal chemistry and organic synthesis, as well as to the treatment of pain-related diseases.