CAS: 206551-41-9; Methyl 3-Bromo-2-Fluorobenzoate

上下游产品

CAS号1007-16-5 3-溴-4-氟苯甲酸 | CAS号74-88-4 碘甲烷 | CAS号161957-56-8 3-溴-2-氟苯甲酸 | CAS号149-73-5 原甲酸三甲酯 | CAS号67-56-1 甲醇 | CAS号77771-03-0 3-溴-4-氟苄胺盐酸盐 | CAS号1195765-45-7 达拉菲尼 | CAS号1195768-18-3 2-氟-3-胺基苯甲醚

3-溴-4-氟苯甲酸,碘甲烷置于potassium Carbonate体系中,用 甲基叔丁基醚,N,N-二甲基甲酰胺 用作溶剂,化学反应 16.0H,以89.5%的收率获得3-溴-2-氟苯甲酸甲酯
参考文献:Wo2007/61930
标题:Wo2007/61930

专利信息

专利号:US-2018065917-A1
优先权日:2016-09-02
标 题 :Immune checkpoint inhibitors, compositions and methods thereof
发明人：WEBBER STEPHEN E; ALMASSY ROBERT J
权利人:POLARIS PHARMACEUTICALS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula (I), or a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof. n n n n n n n n n n For Formula (I) compounds R 1 , R 2 , X 1 , Y 1 and n are as defined in the specification. The inventive Formula (I) compounds are inhibitors of the PD-1/PD-L1 protein/protein binding or functional interaction and find utility in any number of therapeutic applications, including but not limited to treatment of proliferative disorders such as cancer and infectious diseases.

专利号:CN-116139138-A
优先权日:2016-11-11
标题:Heterocyclic regulators of lipid synthesis

专利号:CN-110177551-B
优先权日:2016-11-11
标 题:Heterocyclic modulators of lipid synthesis