CAS: 4163-59-1; A-D-Galactose Pentaacetate

相似化合物

604-69-3 25941-03-1 4163-60-4

上下游产品

β-D-mannose acetic anhydride D-Mannose D-Mannose 1-O-p-nitrophenyl-2,3,4,6-tetra-O-acetyl α-D-mannopyranoside ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-mannopyranoside S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside 1-O-phenyl-2,3,4,6-tetra-O-acetyl-β-D-mannopyranoside

Beta-D-半乳糖五乙酸酯置于四氯化碳,三氟化硼乙醚体系中,用 乙腈 作为反应溶剂,化学反应 0.03H,反应生成 1,2,3,4,6-戊-O-乙酰-A-D-吡喃半乳糖
参考文献:通过光活化自由基反应将β-糖吡喃糖苷转化为α-糖吡喃糖苷
标题:通过光活化自由基反应将β-糖吡喃糖苷转化为α-糖吡喃糖苷
摘要:通过使用四氯化碳作为氯自由基和三氟化硼醚化物作为路易斯酸,实现了糖苷的卤素光活化异头转化.该反应是将糖苷键从β-异头物转化为α-异头物的新颖指导.
DOI:10.1016/j.Tetlet.2016.04.064

专利信息

专利号:WO-0142264-A1
优先权日:1999-12-10
标 题 :Method for the synthesis of sialylated oligosaccharide donors
发明人：MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M
权利人:CA NAT RESEARCH COUNCIL; MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M
摘要:A method for the synthesis of aryl thioglycosides comprising a sialylated residue of β-D-galactose is disclosed. The method consists of preparing by a chemical synthesis a non-sialylated aryl thioglycoside, and enzymatically sialylating the latter with a sialic acid in the presence of a suitable sialyltransferase. The sialylated aryl thioglycoside is then chemically derivatized by standard procedures, to provide a derivative suitable for use as a donor in chemical syntheses of sialylated oligosaccharides. The derivatized sialylated aryl thioglycosides are prepared in high yields, due to reduced number of chemical and purification steps involved in the process. Derivatized aryl thioglycosides useful as building blocks for the synthesis of biologically active sialylated oligosaccharides are also disclosed.

专利号:US-9938312-B2
优先权日:2011-03-25
标题 :Compounds and methods for chemical and chemo-enzymatic synthesis of complex glycans
发明人：BOONS GEERT-JAN; WANG ZHEN
权利人:BOONS GEERT JAN; WANG ZHEN; UNIV GEORGIA
摘要:The present invention provides chemical and chemo-enzymatic methods for the synthesis of a wide array of complex asymmetric multi-antennary glycans.

专利号:US-6723843-B2
优先权日:1996-08-26
标题:Oligosaccharide synthesis
发明人：TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
权利人:ALCHEMIA PTY LTD
摘要:The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to a polymer support. The invention provides reagents, reagent kits and methods for solid-phase oligosaccharide synthesis.

专利号:WO-9636627-A1
优先权日:1995-05-19
标 题 :Collection of activated glycoside compounds and their biological use
发明人：ANDERSON MARK BRIAN; MUSSER JOHN H
权利人:GLYCOMED INC
摘要:The present invention relates to the field of combinatorial carbohydrate chemistry and involves the modification of organic molecules and/or the synthesis of large numbers of products comprising carbohydrate and/or glycominetic entities. More specifically, the present invention relates to activated carbon glycosides useful for the modification of organic molecules by incorporation of carbohydrate units, providing the synthesis of large numbers of products having novel chemical characteristics. The present invention further relates to methods for the generation of chemical compounds comprising carbon glycosides. Methods are disclosed to provide large arrays of molecules and to identify species that act as agonists or antagonists of various biological, chemical, and other activities.

专利号:US-2014051603-A1
优先权日:2011-03-25
标题:Compounds and methods for chemical and chemo-enzymatic synthesis of complex glycans

专利号:WO-9846784-A1
优先权日:1997-04-11
标 题 :Improved synthesis of oligosaccharides using activated glycoside derivatives