CAS: 593-51-1; Methylamine Hydrochloride

上下游产品

methanol formaldehyd trimethylamine hydr°Chloride ephedrine hydr°Chloridethiophene5-methyl-2-(methylamino)methylthiophene N-methyl(1-methyl-1H-pyrrol-2-yl)methylanamine betahistine N-methyl-acetamideN-methyl-acetamide

甲胺置于盐酸体系中,化学反应 3.0H,反应生成 盐酸甲胺
参考文献:溶剂蒸发法在 室温下生长ch 3 Nh 3 Pbcl 3单晶†
标题:溶剂蒸发法在 室温下生长ch 3 Nh 3 Pbcl 3单晶†
摘要:我们报告一个新的路线来合成ch的高品质,大尺寸晶体3 Nh 3 Pbcl 3通过的dsmo-Gbl溶液适当选择经由在室温下溶剂蒸发法.对这些晶体的结构,电子,光学和电学性质进行了详细的评估.我们的xps研究表明,有机-无机卤化物钙钛矿对x射线引起的损害敏感,因此其性质可能会发生变化.另外,光致发光研究显示了两个峰光谱,表明ch 3 Nh 3的有序-无序域共存在样本中.对低缺陷浓度和更长扩散长度的进一步观察表明,通过提出的方法生长的晶体可以为光电子器件提供有希望的解决方案.
DOI:10.1039/c8Ce01939H

专利信息

专利号:US-9090560-B2
优先权日:2013-09-04
标 题 :Process for microwave assisted synthesis of N-methyl pyrrolidone
发明人：KHATRI PRAVEEN KUMAR; JAIN SUMAN LATA; CHATERJEE ALOK KUMAR; BIR SAIN
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to a process for microwave assisted synthesis of N-methyl pyrrolidone (NMP). Particularly the process relates to the synthesis of N-methyl succinimide or corresponding analogs by using microwave irradiation which on hydrogenation in the presence of a hydrogenating catalyst gives N-methyl pyrrolidone. Compared to the conventional heating microwave process requires less energy inputs and reduces the reaction time drastically from 5-6 h to 2-5 min.

专利号:WO-2019202611-A1
优先权日:2018-04-21
标题:An improved process for the synthesis of ivabradine and its pharmaceutically acceptable salts
发明人：NANDEPU Venkateswara Rao; BOPPANA DURGA PRASAD
权利人:METROCHEM API PVT
摘要:: Disclosed herein is an improved process for the preparation of Ivabradine and pharmaceutically acceptable salts thereof. The invention more particularly disclosesthe synthesis of key intermediates viz.,(S)-N-[(4,5-dimethoxybenzocydobut-l-yl)-methyl]-N- (methyl)amine hydrochloride of Formula-II and 3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzapin-2-one of Formula-III, and its use in industrial synthesis of Ivabradine and pharmaceutically acceptable salts thereof.

专利号:WO-2023019298-A1
优先权日:2021-08-20
标 题:Improved method of synthesis of 1-(3',4'-methylene dioxyphenyl)-2-(methylamino) propane (mdma)
发明人：O'MALLEY WILLIAM IAN; WYNNE PAUL MICHAEL
权利人:MIND MEDICINE AUSTRALIA LTD
摘要:The present invention relates to an improved method of synthesis of 1-(3',4'-methylenedioxyphenyl)-2-(methylamino)propane (MDMA) that is of sufficient purity that it can be used for pharmaceutical applications. In particular the present invention provides a method of synthesising MDMA comprising the steps of (a) condensation of piperonal and nitroethane in the presence of a catalysing base to form 1-(3',4'-methylenedioxyphenyl)-2-nitroprop-1-ene (MDP-2-nitropropene), (b) oxidative hydrolysis of MDP-2-nitropropene to form 1-(3',4'methylenedioxyphenyl)-propan-2-one (MDP2P), and (c) reductive amination of MDP2P to 1-(3',4'-methylenedioxyphenyl)-2-(methylamino)propane (MDMA).

专利号:US-5665877-A
优先权日:1993-12-07
标题:Synthesis of bisindolylmaleimides
发明人：FAUL MARGARET M; JIROUSEK MICHAEL R; WINNEROSKI II LEONARD L
权利人:LILLY CO ELI
摘要:The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because it is stereoselective.

专利号:US-5541347-A
优先权日:1993-12-07
标 题 :Synthesis of bisindolylmaleimides
发明人：FAUL MARGARET M; JIROUSEK MICHAEL R; WINNEROSKI II LEONARD L
权利人:LILLY CO ELI
摘要:The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because it is stereoselective.

专利号:US-12240835-B2
优先权日:2018-09-18
标题:Substituted benzamides as intermediates in the synthesis of inhibitors of tyrosine kinase enzymatic activity
发明人：ROMERO F ANTHONY; KIRSCHBERG THORSTEN A; HALCOMB RANDALL; XU YINGZI
权利人:TERNS PHARMACEUTICALS INC
摘要:Provided herein are compounds, preferably compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, compositions thereof, and methods of their preparation, and methods of inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, and methods for treating diseases wherein modulation of BCR-ABL1 activity prevents, inhibits, or ameliorates the pathology and/or symptomology of the disease. Intermediates such as compounds of Formula (S23), which are useful in the synthesis of compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, are also provided.