CAS: 7429-44-9; 2-Methoxycyclohexanone

相似化合物

533-60-8 13482-23-0 155320-76-6

上下游产品

cyclohexanone-2-ol methanol N-benzylcyclohexylimine 1-cyclohexenyl acetate cyclohexane-1,2-dione-bis-(2,4-dinitro-phenylhydrazone) 1-butyl-2-methoxy-cyclohexanol 2-methoxy-1-methylcyclohexanol 2-Methoxy-α-phenylcyclohexan-1-ol

木榴油置于c33H49Clnrh,氢气体系中,用 2,2,2-三氟乙醇,水 作为反应溶剂,70.0 °C,5.0 Mpa 条件下,反应 24.0H,以71%的收率获得产物2-甲氧基环己酮
参考文献:环状(氨基)(烷基)卡宾铑配合物实现芳香酮和酚的高选择性氢化
标题:环状(氨基)(烷基)卡宾铑配合物实现芳香酮和酚的高选择性氢化
摘要:由强 σ 供体环状(氨基)(烷基)卡宾 (Caac) 连接的空气稳定的 Rh 配合物通过还原芳基显示出独特的催化活性,可用于芳香酮和苯酚的选择性氢化.caac 配体的使用对于实现高选择性和转化率至关重要.该方法的特点是与不饱和酮,酯,羧酸,酰胺和氨基酸具有非常好的相容性,并且可以在不影响其效率的情况下进行扩展.
DOI:10.1021/jacs.5B05868

专利信息

专利号:US-6720439-B1
优先权日:2001-09-28
标题:Synthesis of ruthenium-hydride complexes and preparation procedures of chiral alcohols and ketones
发明人：OHKUMA TAKESHI; KOIZUMI MASATOSHI; MUNIZ KILIAN; NOYORI RYOJI
权利人:INST NAGOYA IND SCIENCE RES
摘要:trans-RuH(eta<1>-BH4)[(S)-xylbinap][(S,S)-dpen] (0.00125 mmol), acetophenone (5.0 mmol), and 2-propanol (2.5 mL) were placed in an autoclave, and the resulting solution was repeatedly subject 5 times to a procedure of performing pressure reduction and argon introduction while stirring the solution for deaeration. A hydrogen tank was then connected to the autoclave, and after replacing the air inside an introduction tube with hydrogen, the pressure inside the autoclave was adjusted to 5 atmospheres and then hydrogen was released until the pressure dropped to 1 atmosphere. After repeating this procedure 10 times, the hydrogen pressure was adjusted to 8 atmospheres and stirring at 25° C. was performed for 12 hours. By concentrating the solution obtained by depressurization and subjecting the crude product to simple distillation, (R)-1-phenylethanol (yield: 95%) in the form of a colorless oily substance was obtained at an ee of 99%.

专利号:US-4215044-A
优先权日:1979-04-23
标题:Synthesis of α-fluorocarbonyl compounds
发明人：MIDDLETON WILLIAM J
权利人:DU PONT
摘要:Process for preparing an organic compound of the formula R 2 R 2 CFC(O)R 3 , which process comprises contacting and reacting in a reaction mixture which includes an inert solvent, at a temperature of -40° C. to -100° C., ROF and ##STR1## R is polyfluoroperhaloalkyl of 1-6 carbon atoms or FOCF 2 ; R 1 is hydrocarbyl of 1-6 carbon atoms; n each R 2 is selected from H, alkyl of 1-17 carbon atoms, cycloalkyl of 3-6 carbon atoms, aryl, heteroaryl and such alkyl, cycloalkyl, aryl and heteroaryl substituted by halogen or alkoxy of 1-6 carbon atoms; n R 3 is selected from H, alkyl and haloalkyl of 1-16 carbon atoms, cycloalkyl of 3-10 carbon atoms, aryl and haloaryl, OSi(R 1 ) 3 , OH, NH 2 , alkoxy of 1-6 carbon atoms, aryloxy, NHR 1 and NR 1 2 wherein R 1 is alkyl of 1-6 carbon atoms, N-arylamino and nitrogen or sulfur heterocyclic of 4-5 carbon atoms; n R 3 and one R 2 taken together is a diradical which with the Câ•?C group is carbocyclic, heterocyclic or haloheterocyclic, and recovering from the reaction mixture the compound of the formula R 2 R 2 CFC()R 3 .