CAS: 150-86-7; (7R,11R,E)-3,7,11,15-Tetramethylhexadec-2-En-1-Ol

相似化合物

7541-49-3 10236-16-5 106-24-1

上下游产品

E,7R,11R)-3,7,11,15-tetramethyl-hexadec-2-enoic acid methyl ester(2E,7R,11R)-3,7,11,15-tetramethyl-hexadec-2-enoic acid methyl ester Z,7R,11R)-3,7,11,15-tetramethyl-hexadec-2-enoic acid ethyl ester(2Z,7R,11R)-3,7,11,15-tetramethyl-hexadec-2-enoic acid ethyl ester 2-methyl-3,4-epoxy-1-butene (3R,7R)-3,7,11-Trimethyldodecylmagnesium-bromidR:11R)-trans-phytyl)-hydroquinone2.3.5-trimethyl-6-((7R:11R)-trans-phytyl)-hydroquinone phytomenadione 2-methyl-3-phytyl-1,4-naphthalenediol dl-δ-t°Copherol

(E)-(7R,11R)-1-(1'-Ethoxy)Ethoxy-3,7,11,15-Tetramethyl-2-Hexadecene置于盐酸,氯化铵体系中,用 四氢呋喃 用作溶剂,化学反应 3.0H,以68%的收率获得植物醇
参考文献:贝克酵母通过双键还原立体选择性全合成天然植物醇
标题:贝克酵母通过双键还原立体选择性全合成天然植物醇
摘要:天然(e)-(7R,11R)-苯酚(1)是叶绿素分子的成分,维生素k1(2)和其他天然化合物,是通过li 2 Cucl 4诱导的对映体和非对映体纯形式合成的两个c 10-单元(8,12).这两个单元都是由香叶醇(3)通过活化的双键的酶促对映选择性氢化制备的.
Doi:10.1016/s0040-4020(01)90325-4

专利信息

专利号:EP-1309698-B1
优先权日:2000-07-21
标 题:A cytochrome p450 enzyme associated with the synthesis of delta-12 -epoxy groups in fatty acids of plants
发明人：CAHOON EDGAR B
权利人:DU PONT
摘要:An isolated nucleic acid fragment encoding a cytochrome P450 enzyme associated with the synthesis of plant DELTA12-epoxy fatty acids is disclosed. The invention also relates to making a chimeric construct encoding all or a portion of the cytochrome P450 enzymes associated with the synthesis of plant DELTA12-epoxy fatty acids, in sense or antisense orientation, wherein expression of the chimeric construct results in production of altered levels of the cytochrome P450 enzymes associated with the synthesis of plant DELTA12-epoxy fatty acids in a transformed host cell.

专利号:US-4125735-A
优先权日:1975-03-20
标 题 :Synthesis of esters of acetylenic alcohols
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of perfume products, Vitamin E and intermediates described herein involving a coupling reaction. For instance, a process for the synthesis of dehydrophytol and Vitamin E comprising forming a C15 acetylene from hexahydropseudoionone and then coupling said acetylene with 1-acetoxy-4-chloro-3-methylbut-2-ene to form a C20 acetoxy-enyne. The latter is readily subjected to partial hydrogenation and saponification in that order to form a dehydrophytol, a useful intermediate for the synthesis of Vitamin E and other products.

专利号:US-6451543-B1
优先权日:1998-08-31
标题:Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
发明人：KOCHENDOERFER GERD G; HUNTER CHRISTIE L; KENT STEPHEN B H; BOTTI PAOLO
权利人:GRYPHON SCIENCES
摘要:The present invention relates to methods and compositions for lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides that are incorporated in a lipid matrix. The invention is exemplified in production of a prefolded membrane polypeptide embedded within a lipid matrix via stepwise chemoselective chemical ligation of unprotected peptide segments, where at least one peptide segment is embedded in a lipid matrix. Any chemoselective reaction chemistry amenable for ligation of unprotected peptide segments can be employed. Suitable lipid matrices include liposomes, micelles, cell membrane patches and optically isotropic cubic lipidic phase matrices. Prefolded synthetic and semi-synthetic membrane polypeptides synthesized according to the methods and compositions of the invention also permit site-specific incorporation of one or more detectable moieties, such as a chromophore, which can be conveniently introduced during synthesis. The methods and compositions of the invention have multiple uses. For example, they can be used to assay ligand binding to membrane polypeptides and domains comprising a receptor, and thus are extremely useful for structure/function studies, drug screening/selection/design, and diagnostics and the like, including high-throughput applications. The methods and compositions of the invention are particularly suited for FRET analyses of previously inaccessible membrane polypeptides.

专利号:US-4039591-A
优先权日:1975-03-20
标 题:Synthesis of dehydrophytol and Vitamin E
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of dehydrophytol and Vitamin E comprising forming a C15 acetylene from hexahydropseudoionone and then coupling said acetylene with 1-acetoxy-4-chloro-3-methylbut-2-ene to form a C20 acetoxy-enyne. The latter is readily subjected to partial hydrogenation and saponification in that order to form a dehydrophytol, a useful intermediate for the synthesis of Vitamin E and other products.

专利号:US-4115466-A
优先权日:1975-10-16
标题:Synthesis of acetylenic compounds useful in preparing dehydrophytols and Vitamin E
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of an acetylenic hydrocarbon from an acetylenic carbinol which involves first replacing the hydroxyl group of the carbinol with a halogen to form a propargylic halide, dehalogenating the propargylic halide to form an allene, and isomerizing said allene to the desired acetylene. The present invention is particularly useful in the synthesis of Vitamin E.

专利号:US-4000169-A
优先权日:1975-01-27
标题 :Asymmetric synthesis of optically active compounds
发明人：CHAN KA-KONG; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.