CAS: 16817-43-9; 5-Bromo-2-Chloroanisole

相似化合物

174913-11-2 427886-20-2 50638-47-6

上下游产品

4-bromo-1,2-dichlorobenzene sodium methylate 5-bromo-2-chlorophenol dimethyl sulfate 4-chloro-3-methoxybenzonitrile 4-chloro-3-methoxybenzophenone lithium 4-chloro-3-methoxy-benzene-sulfinate 3-methoxy-4-pyrrolidinobenzophenone

苯置于氢氧化钾,三氯化铝体系中,化学反应生成5-溴-2-氯苯甲醚
参考文献:苯和氯化铝对四卤代苯酚的作用.
标题:苯和氯化铝对四卤代苯酚的作用.
摘要:
Doi:10.1021/jo01166A001

专利信息

专利号:US-5670666-A
优先权日:1993-09-27
标题:Process for preparing intermediates for the synthesis of D1 antagonists
发明人：HOU DONALD; DRAPER RICHARD W; LEE GARY M; MAS JANET L
权利人:SCHERING CORP
摘要:Disclosed are a process and intermediates of the formulae ##STR1## wherein X - is halide, BF 4 - , R 3 SO 3 - , wherein R 3 is C 1 -C 6 alkyl, CF 3 , C 1 -C 6 alkylphenyl or phenyl, and Q is a group of the formula ##STR2## wherein R is C 1 -C 6 alkyl; useful for preparing benzazepine intermediates of the formula ##STR3## These benzazepine intermediates are useful for preparing benzazepines having activity as selective D1 receptor antagonists.

专利号:US-5502186-A
优先权日:1993-09-27
标 题:Process for preparing intermediates for the synthesis of D1 antagonists
发明人：HOU DONALD; DRAPER RICHARD W; LEE GARY M; MAS JANET L
权利人:SCHERING CORP
摘要:Disclosed are a process and intermediates of the formula ##STR1## wherein R is --CH 3 or --C(O)--OR 1 , and R 1 is C 1 -C 6 alkyl or --CH 2 C 6 H 5 ; or the formula ##STR2## wherein: R 2 is H or OH, R is --C(O)OR 1 and R 1 is C 1 -C 6 alkyl or --CH 2 C 6 H 5 , or where R 2 is H, R can also be CH 3 ; for preparing benzazepine intermediates of the formula ##STR3## The benzazepine intermediates are useful for preparing benzazepines having activity as selective D1 receptor antagonists.

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

专利号:WO-9509156-A1
优先权日:1993-09-27
标 题 :Processes and intermediates for the enantiospecific synthesis of benzo(d)naphth(2.1-b)azepines

专利号:WO-9509155-A2
优先权日:1993-09-27
标题:Process and intermediates for the enantiospecific synthesis of benzo [d]naphth[2,1-b]azepines

专利号:US-5461147-A
优先权日:1993-09-27
标题 :Process for preparing benzazepine intermediates for the synthesis of D1 antagonists