CAS: 1779-60-8; Acetoacetic Acid N-Propyl Ester

该化合物是被归类为乙基酯的有机化合物,其特征为与乙基乙酸酯混合物相连的丙基酰组,由一个酮和一个酯功能组组成,该化合物一般没有颜色可粉黄,具有水果味,可用于调味和香味应用;丙烯丙烯乙酸酯在乙醇和乙醚等有机溶剂中可溶解,但因其水中的缺水性丙基化合物组而限制溶性;已知该化合物在各种化学反应中具有再活动性,包括克莱森凝结和迈克尔,在合成有机化学中具有价值;此外,该化合物可作为合成药物和农用化学物的中间体;安全数据表明,应当谨慎处理该物质,因为它可能会引起皮肤和眼睛的刺激.

结构式图片

相似化合物

141-97-9 591-60-6 6624-84-6

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上下游产品

CAS号71-23-8 正丙醇 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号105-45-3 乙酰乙酸甲酯 | CAS号5394-63-8 2,2,6-三甲基-4H-1,... | CAS号591-60-6 乙酰乙酸丁酯 | CAS号109-60-4 醋酸正丙酯 | CAS号75-36-5 乙酰氯 | CAS号2911-21-9 6-methyl-1,3-ox... | CAS号674-82-8 双乙烯酮 | CAS号591-60-6 乙酰乙酸丁酯 | CAS号69578-90-1 propyl (3E)-3-[... | CAS号77888-04-1 propyl 2-[(3-ni... | CAS号86781-09-1 propyl cyclopro...

合成工艺路线路线简述

    乙酸丙酯置于乙醚,氨,Sodium Amide体系中,化学反应生成乙酰乙酸正丙酯
    参考文献:Shivers; Dillon; Hauser,Journal Of The American Chemical Society,1947,Vol. 69,P. 120
    标题:Shivers; Dillon; Hauser,Journal Of The American Chemical Society,1947,Vol. 69,P. 120

    海关参考信息

    专利信息


    专利号:US-10487099-B2
    优先权日:2017-06-30
    标 题:Synthesis of hypervalent iodine reagents with dioxygen
    发明人:POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN
    权利人:TEXAS A & M UNIV SYS
    摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.

    专利号:WO-2016173960-A1
    优先权日:2015-04-29
    标 题 :Optimized synthesis of pregabalin and 4-aminobutane acid using an improved method for producing conjugated nitroalkenes
    发明人:STUMPF MARCUS
    权利人:K H S PHARMA HOLDING GMBH
    摘要:The invention relates to an optimized synthesis of pregabalin and additional 4-aminobutane acids using an improved method for producing conjugated nitroalkenes. This is achieved by a nitro-aldol reaction of an aliphatic aldehyde with a nitroalkane in the presence of a suitable diamine directly followed by an elimination of the conjugated nitroalkene by adding an acid, a subsequent catalyzed asymmetrical 1,4-Michael addition of a suitable nucleophile, and a subsequent retro-Claisen reaction or a hydrolosis and decarboxylation with a concluding reduction to 4-aminobutane acid.

    专利号:US-2004249219-A1
    优先权日:2000-07-05
    标题 :Method of making teprenone
    发明人:SAUCY GABRIEL G
    摘要:The invention is directed to an efficient and economical method of making teprenone. Teprenone is synthesized by converting geranylgeraniol to teprenone by a novel route. The method of synthesis can begin with geranylgeraniol obtained from a biological source such as fermentation of a microorganism capable of producing geranylgeranyl or enzymatic synthesis in a cell free system to produce predominantly the 5E isomer of teprenone. The chemical synthesis proceeds with retention of configuration such that the teprenone produced has the isomeric configuration of the geranylgeraniol starting material.

    专利号:CN-116904543-A
    优先权日:2023-09-07
    标 题:Application and synthesis method of a dehydrogenase in the synthesis of R-configuration Boseine

    专利号:CN-116904543-B
    优先权日:2023-09-07
    标 题:Application and synthesis method of a dehydrogenase in the synthesis of R-configuration Boseine

    专利号:EP-3088383-A1
    优先权日:2015-04-29
    标题:Optimized synthesis of pregabalin and 4-amino butanoic acid using an improved production method of conjugated nitroalkenes
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    合成参考文献


    摘要:Iesce, M. R.; DellaGreca, M., Science of Synthesis, (2009) 38, 234.
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