CAS: 214210-30-7; 4-Bromo-2-Fluorobenzenesulfonamide

上下游产品

4-bromo-2-fluorobenzenesulfonyl chloride 4-bromo-N-(4,4'-dimethoxytrityl)-2-fluorobenzenesulfonamide 2-fluorobenzenesulfonamide 4-bromo-2-(cyclohexyloxy)benzenesulfonamide

4-溴-2-氟苯磺酰氯置于ammonium Hydroxide,Sodium Hydroxide体系中,用 乙腈 用作溶剂,化学反应生成4-溴-2-氟苯磺酰胺
参考文献: Pyrazole-Substituted Cyclopentanol Ester Derivative And Use Thereof[fr] Dérivé D'Ester De Cyclopentanol Substitué Par Pyrazole Et Son Utilisation[zh] 一种吡唑取代环戊酯衍生物及其用途
标题: Pyrazole-Substituted Cyclopentanol Ester Derivative And Use Thereof[fr] Dérivé D'Ester De Cyclopentanol Substitué Par Pyrazole Et Son Utilisation[zh] 一种吡唑取代环戊酯衍生物及其用途
摘要:本申请涉及一种吡唑取代环戊酯衍生物及其用途,具体涉及式(I)所示化合物,其异构体或其药学上可接受的盐.

专利信息

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.