CAS: 224311-51-7; 2-(Di-Tert-Butylphosphino)Biphenyl

上下游产品

CAS号13716-10-4 二叔丁基氯化膦 | CAS号82214-69-5 2-联苯基溴化镁 | CAS号1336-21-6 氨水 | CAS号2052-07-5 邻溴联苯 | CAS号819-19-2 二叔丁基膦 | CAS号17763-65-4 (2-phenylphenyl... | CAS号583-55-1 2-溴碘苯 | CAS号98-80-6 苯硼酸 | CAS号854045-93-5 氯[2-(二叔丁基磷)二苯基]金 | CAS号7372-85-2 2,5-DIMETHYLBIPHENYL | CAS号92495-53-9 1-methoxy-2-(4-... | CAS号3976-34-9 2,6-DIMETHYLBIPHENYL | CAS号412348-60-8 1-B°C-4-(5-溴吡啶-...

邻碘溴苯置于bis-Triphenylphosphine-Palladium(II) Chloride,正丁基锂,Potassium Carbonate体系中,用 乙二醇二甲醚,乙醚,正己烷,水 用作溶剂,化学反应 8.0H,反应生成2-(二叔丁基膦)联苯
参考文献:钯催化的p(o)r2指导ch芳基化反应合成富电子的多芳族单磷配体.
标题:钯催化的p(o)r2指导ch芳基化反应合成富电子的多芳族单磷配体.
摘要:报道了p(o)r2指导的ch官能团的钯催化的(二异丙基磷酰基)联苯骨架衍生物的芳基化.获得的相关产物具有较高的区域选择性,并且观测到非常好的官能团耐受性.该反应为合成多芳族单磷配体提供了新的有效途径.
Doi:10.1039/c3Cc49050E

专利信息

专利号:WO-2025119975-A1
优先权日:2023-12-04
标 题:A method for synthesis of harmine
发明人：HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN
权利人:RECONNECT LABS AG
摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-8288581-B2
优先权日:2008-07-17
标 题:Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO
权利人:PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO; SERVIER LAB; CENTRE NAT RECH SCIENT
摘要:Process for the preparation of compounds of formula (IV): n nwherein R 1 -R 6 are as defined in the specification.n n Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:US-7632975-B2
优先权日:2004-12-22
标 题:Process for the synthesis of arylfluorenes and analogs thereof
发明人：HEIDENHAIN SOPHIE
权利人:CDT OXFORD LTD
摘要:A process is provided for the synthesis of a compound of formula (I): n nwherein:n M=0 or 1; N and p are 0 or 1 to 4; X is a single bond, O, S or NH; And R 1 -R 4 are as defined in claim 1.

专利号:US-8058477-B2
优先权日:2006-03-21
标 题 :Process for the synthesis of arylamines from the reaction of an aromatic compound with ammonia or a metal amide
发明人：HARTWIG JOHN F; SHEN QILONG
权利人:HARTWIG JOHN F; SHEN QILONG; UNIV YALE
摘要:A catalytic process for the synthesis of aromatic primary amines, reagent compositions for effecting the process, and transition metal complexes useful in the process, are provided.

专利号:US-6958420-B2
优先权日:2002-07-19
标题:Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL
权利人:UNIV MICHIGAN STATE
摘要:A process is described for synthesizing aminoarylboronic esters of the general formula n n nwherein R, R 2 , and R 3 are each an alkyl, aryl, vinyl, alkoxy, carboxylic esters, amides, or halogen; Ar is any variety of phenyl, naphthyl, anthracyl, heteroaryl; and R 1 is alkyl, hydrogen, or aryl. The aminoarylboronic esters are produced via the metal-catalyzed coupling of arylboronic esters of the general formula n n nwherein R and R 1 are any non-interfering group and X is chloro, bromo, iodo, triflates, or nonaflates to amines (primary and secondary). In particular, a process is described for the synthesis of the aminoarylboronic esters via a step-wise or tandem process in which one catalytic event is a metal-catalyzed borylation and the other catalytic event is a metal-catalyzed amination.