专利号:US-4216159-A 优先权日:1978-05-25 标题 :Synthesis of 16-unsaturated pregnanes from 17-keto steroids 发明人:HESSLER EDWARD J; VANRHEENEN VERLAN H 权利人:UPJOHN CO 摘要:17-Keto steroids (I) in their protected form (IIa or IIb) are reacted with a metalated olefin (VI) to give a 21-aldehyde (IV) which is readily transformed to a 16-unsaturated pregnane (V) which is useful in the production of commercially important substituted corticoids.
专利号:US-7109007-B2 优先权日:1987-06-29 标题 :Polyhydroxybutyrate polymerase 发明人:PEOPLES OLIVER P; SINSKEY ANTHONY J 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:A method for controlling and modifying biopolymer synthesis by manipulation of the genetics and enzymology of synthesis of polyhydroxybutyrate (PHB) and polyhydroxyalkanoate (PHA) polyesters at the molecular level in procaryotic and eukaryotic cells, especially plants. Examples demonstrate the isolation, characterization, and expression of the genes involved in the production of PHB and PHA polymers. Genes encoding the enzymes in the PHB and PHA synthetic pathway (beta-ketothiolase, acetoacetyl-CoA reductase and PHB polymerase or PHA polymerase) from Zoogloea ramigera strain I-16-M, Alcaligenes eutrophus, Nocardia salmonicolur , and Psuedomonas olevarans were identified or isolated and expressed in a non-PHB producing organism, E. coli . Specific modifications to the polymers include variation in the chain length of the polymers and incorporation of different monomers into the polymers to produce co-polymers with different physical properties.
专利号:US-5250430-A 优先权日:1987-06-29 标题 :Polyhydroxyalkanoate polymerase 发明人:PEOPLES OLIVER P; SINSKEY ANTHONY L 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:A method for controlling and modifying biopolymer synthesis by manipulition of the genetics and enzymology of synthesis of polyhydroxybutyrate (PHB) and polyhydroxyalkanoate (PHA) polyesters at the molecular level in procaryotic and eukaryotic cells, especially plants. Examples demonstrate the isolation, characterization, and expression of the genes involved in the production of PHB and PHA polymers. Genes encoding the enzymes in the PHB and PHA synthetic pathway (beta-ketothiolase, acetoacetyl-CoA reductase and PHB polymerase or PHA polymerase) from Zoogloea ramigera strain I-16-M, Alcaligenes eutrophus, Nocardia salmonicolur, and Psuedomonas olevarans were identified or isolated and expressed in a non-PHB producing organism, E. coli. Specific modifications to the polymers include variation in the chain length of the polymers and incorporation of different monomers into the polymers to produce co-polymers with different physical properties.
专利号:US-2023097824-A1 优先权日:2020-05-08 标 题:Semi-synthesis and use of racemic hematoxylin 发明人:DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR 权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC 摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.
专利号:US-10772990-B2 优先权日:2014-04-01 标题 :Tissue filler compositions and methods of use 发明人:NIKOLIS ANDREAS; HERBERT LISE 权利人:KLOX TECH INC 摘要:The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.
专利号:US-4536776-A 优先权日:1981-10-05 标题:Ink-jet printing device 发明人:KNIRSCH FRANCO; GIANOLINI GIOVANNI; DAGNA GIAN D; BUAT MARIO 权利人:OLIVETTI & CO SPA 摘要:The device comprises a plurality of ink reservoirs, each connected to a number of nozzles (22) equidistant along a corresponding row. The nozzles connected to the various reservoirs are spaced apart vertically by at least one line space. The device can be used for printing different lines in parallel, moreover subdividing the length of the line, or for printing different zones of the sheet in facsimile. The ink is kept in circulation between the reservoirs and the nozzles by a common peristaltic pump which acts by a series of actuating elements on the discharge ducts for the inks in the reservoirs. The reservoirs may contain inks of different colors to permit printing in different colors or polychrome facsimile printing by additive or subtractive synthesis of the colors. The ink is conductive and is kept at earth potential, while electrodes (23) disposed outside the corresponding nozzles (22) are energized selectively to produce sprays of particles of ink from the nozzles. The ink contains a mixture of a dye of direct or solvent or acid type with a solution of water, electrolytic compounds, moistening agents, thickeners, preserving agents and antifoaming agent. The ink is prepared by mixing the compounds under agitation, then mixing in the dye until a predetermined acidity is obtained and finally filtering it and sealing it in the pack in the absence of air.
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合成参考文献
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