CAS: 15854-87-2; 4-Iodopyridine

该化合物是一种有机化合物,其特点是,一种配有碘原子的有机化合物,附着于一个环的第四位置上,这是含有一个氮原子的由六人组成的芳香热循环,分子式为C5H4N I,其分子量为C5H4N I,其分子量为分子量,反映其组成原子的贡献.该化合物一般呈现无色的轻黄色液体或固体,视其形态和纯度而定.4-Iodopyridine在有机合成中的作用而著称,特别是作为各种药品和农用化学品制作的建筑块.它显示出极地有机溶剂中具有中度溶性,并由于碘原子的存在而可参与核分裂性替代反应,而该原子可能因核素的分离而转移.此外,它可能在特定条件下表现出某种程度的再活性,使其成为合成化学中有价值的中间体.在处理该化合物时,应注意安全防范,因为如果浸入或吸入,可能会对健康造成危害.

结构式图片

相似化合物

53710-18-2 83674-72-0 18820-83-2

欧盟法规

ECHA物质C&L通报

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CAS号110-86-1 吡啶 | CAS号504-24-5 4-氨基吡啶 | CAS号626-61-9 4-氯吡啶 | CAS号1120-87-2 4-溴吡啶 | CAS号7379-35-3 4-氯吡啶盐酸盐 | CAS号19524-06-2 4-溴吡啶盐酸盐 | CAS号10034-85-2 氢碘酸 | CAS号126179-78-0 methyl3-(pyridi... | CAS号106047-17-0 4-(吡啶-4-基)苯甲酸甲酯 | CAS号106047-16-9 methyl 2-pyridi... | CAS号5938-16-9 4-(4-甲氧基苯基)吡啶 | CAS号4373-68-6 Pyridine,4-(3-m... | CAS号54401-85-3 4-吡啶乙酸乙酯 | CAS号33974-27-5 苯基(4-吡啶基)甲醇 | CAS号49826-70-2 4-苄氧基吡啶 | CAS号37968-97-1 4,4'-联吡啶硫

合成工艺路线路线简述

    4-氯吡啶置于trimethylstannylsodium,碘体系中,化学反应生成4-碘吡啶
    参考文献:Yamamoto,Yukata; Yanagi,Akihiko,Chemical And Pharmaceutical Bulletin,1982,Vol. 30,# 5,P. 1731-1737
    标题:Yamamoto,Yukata; Yanagi,Akihiko,Chemical And Pharmaceutical Bulletin,1982,Vol. 30,# 5,P. 1731-1737

    海关参考信息

    专利信息


    专利号:US-8569560-B2
    优先权日:2006-10-13
    标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis
    发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J
    权利人:ELEVANCE RENEWABLE SCIENCES
    摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.

    专利号:US-9255117-B2
    优先权日:2006-07-13
    标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis
    发明人:SCHRODI YANN
    权利人:MATERIA INC
    摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.

    专利号:US-10927135-B2
    优先权日:2017-08-03
    标 题:Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates
    发明人:KANG JUN YONG; HUANG HAI
    权利人:THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIV OF NEVADA LAS VE
    摘要:Provided herein are phosphates, thiophosphates, phosphonates, and phosphinates, methods of making same, and methods of using these compounds and methods for the generation of pharmaceutically relevant phosphate, phosphonate, and phosphinate analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    专利号:US-6946533-B2
    优先权日:2002-08-01
    标 题 :Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers
    发明人:GRUBBS ROBERT; BIELAWSKI CHRIS; BENITEZ DIEGO
    权利人:CALIFORNIA INST OF TECHN
    摘要:A method for synthesizing cyclic polymers using transition metal alkylidene complexes as reaction catalysts is provided, wherein the complexes contain a cyclic group. Polymerization is carried out on the catalyst, using cyclic olefin monomers that undergo ring insertion polymerization, and no linear intermediates are generated. Following completion of polymerization, the cyclic polymer detaches from the complex via an intramolecular chain transfer reaction and the catalytic complex is regenerated. The invention also provides novel transition metal alkylidene complexes useful as catalysts in the aforementioned process, as well as novel cyclic hydrocarbons.

    专利号:US-11794179-B2
    优先权日:2016-08-24
    标 题 :Synthesis and characterization of metathesis catalysts
    发明人:JOHNS ADAM M
    权利人:UMICORE AG & CO KG
    摘要:This invention relates generally to olefin metathesis catalysts, to the preparation of such compounds, compositions comprising such compounds, methods of using such compounds, and the use of such compounds in the metathesis of olefins and in the synthesis of related olefin metathesis catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and in industrial applications such as oil and gas, fine chemicals and pharmaceuticals.

    专利号:US-2025026871-A1
    优先权日:2021-04-06
    标 题:Cyclic ruthenium benzylidene initiators for enhanced ring expansion metathesis polymerization
    发明人:GOLDER MATTHEW; WANG TENG-WEI; JOHNSON JEREMIAH A
    权利人:UNIV WASHINGTON; MASSACHUSETTS INSTITUTE OF TECH M I T; MASSACHUSETTS INST TECHNOLOGY
    摘要:Cyclic ruthenium benzylidene initiators useful for the controlled synthesis of functionalized cyclic macromolecules via ring-expansion metathesis polymerization.
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    合成参考文献


    摘要:Mérour, J.-Y.; Joseph, B., Science of Synthesis Knowledge Updates, (2016) 3, 470.
    摘要:Gao, W.-C.; Tian, J., Science of Synthesis Knowledge Updates, (2020) 3, 297.
    摘要:Scholz, U.; Dong, W.; Feng, J.; Shi, W., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 68.
    摘要:Scholz, U.; Dong, W.; Feng, J.; Shi, W., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 89.
    摘要:Phelps, A. M.; Alderson, J. M.; Schomaker, J. M., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 1, 341.
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