CAS: 2127-03-9; 1,2-Di(Pyridin-2-yl)Disulfane

相似化合物

15658-35-2 2127-10-8 872273-36-4

上下游产品

CAS号2637-34-5 2-巯基吡啶 | CAS号7758-19-2 亚氯酸钠 | CAS号109-04-6 2-溴吡啶 | CAS号108-86-1 溴苯 | CAS号122334-49-0 2-thioxopyridin... | CAS号292638-85-8 丙烯酸甲酯 | CAS号73322-01-7 1-NITRO-4-(2-PY... | CAS号76410-88-3 n-butyl 2-pyrid... | CAS号2637-34-5 2-巯基吡啶 | CAS号10002-30-9 phenyl-pyridin-... | CAS号4783-68-0 2-苯氧基吡啶 | CAS号91-60-1 2-巯基萘 | CAS号24367-35-9 2-(phenyldisulf... | CAS号24210-19-3 (S)-2-(((苄氧基)羰基... | CAS号68617-64-1 3-(2-吡啶二硫代)丙酸 | CAS号13616-82-5 2,4-二甲基苯硫酚 | CAS号791-28-6 三苯基氧化膦 | CAS号106-54-7 4-氯苯硫酚

2-肼基吡啶盐酸盐置于1,2,3,4,5,6,7,8-八硫杂环辛烷,氧气,Sodium Hydroxide体系中,用 水,乙腈 用作溶剂,70.0 °C,300.01 Kpa 条件下,反应 12.0H,以92%的收率获得2,2'-二硫二吡啶
参考文献:一种以芳基肼与s
标题:一种以芳基肼与s
摘要:本发明涉及一种以芳基肼与s8为原料合成对称二硫化合物的方法,属于有机合成技术领域,该方法以芳基肼类化合物和s8为底物,在碱的促进下,在反应溶剂中反应生成对称二硫有机化合物,反应的气体氛围为空气或氧气,反应温度为40oc‑100°C,反应时间为4‑24H.本发明合成步骤简单,反应条件温和,采用自然界分布广泛,廉价易得的s8作为硫源,无需过渡金属催化,仅在碱的促进下即可构建s‑s键,产率高达95%,所适用的反应底物范围广泛,操作简单易行,合成成本低廉,对环境污染小,为对称二硫有机化合物的合成提供了一种新思路.

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-5549974-A
优先权日:1994-06-23
标题:Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:The invention provides an efficient and versatile method for the combinatorial synthesis and screening of libraries of 4-thiazolidinones, metathiazanones, and derivatives thereof. In order to expediently synthesize a combinatorial library of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. Arrays of thiazolidinones, metathiazanones, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antihistaminic, or antimicrobial activity or use in the treatment of inflammation, hypertension, renal failure, congestive heart failure, uremia and other conditions can be prepared using this method.

专利号:US-2016075680-A1
优先权日:2013-04-30
标题:Modified solid support for the synthesis of oligonucleotides
发明人：SOMOZA CALATRAVA ALVARO; LATORRE LOZANO ALFONSO
权利人:FUNDACIÓN IMDEA NANOCIENCIA; FUNDACION IMDEA NANOCIENCIA
摘要:The present invention refers to a new solid support for the synthesis of oligonucleotides, to a method for its preparation and to its use in the solid phase synthesis of oligonucleotides.

专利号:US-5817751-A
优先权日:1994-06-23
标 题 :Method for synthesis of diketopiperazine and diketomorpholine derivatives
发明人：SZARDENINGS ANNA KATRIN; CAMPBELL DAVID
权利人:AFFYMAX TECH NV
摘要:The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such methods to create libraries of diverse diketopiperazine derivatives. The present invention has application in the areas of chemical synthesis, the screening for new diketopiperazine derivatives having beneficial medical properties and the use of such screening to provide compositions and methods including diketopiperazine derivatives for treating disease.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.