CAS: 873-69-8; 2-Pyridinealdoxime

• 英文名称2-Pyridinealdoxime
• 中文名称吡啶醛肟
• IUPAC名称(E)-picolinaldehyde oxime
• 其它别名Tert-Butyl(Trans-3-Hydroxycyclobutyl)Methylcarbamate; 2Wfo9N5Mqe; Pyridine-2-Carboxaldehyde Oxime; Syn-Pyridin-2-Aldoxime; 2-Pyridinecarbaldehyde Oxime; 2-Pyridinecarboxaldehyde, Oxime, (C(E))-; Pyridine-2-Ald
• CAS编号873-69-8
• MFCD编号:MFCD00006354
• EINECS号:212-849-6
• 分子式:C6H6N2O
• 分子量:122.12
• 产品CID: 1880176
• 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: MTFJSAGADRTKCI-UHFFFAOYSA-N
• InChI=1S/C6H6N2O/c9-8-5-6-3-1-2-4-7-6/h1-5,9H/b8-5+…
• 计算化学: 氢键受体数3.0氢键供体数1可旋转键数1

相似化合物

物理性质

• 熔点110-112  °C(文献)
• 沸点233.1±13.0 °C at 760 mmHg
• 闪点94.8±19.8 °C
• 密度1.1±0.1 g/cm3
• PH:7 (20°C, 13g/L in H2O)
• pKa:pK1: 3.42(+1);pK2: 10.22(0) (25°C)
• PSA:45.48
• LogP:0.8897
• 折射率1.560
• 蒸汽压0.0±0.5 mmHg at 25°C
• 溶解性Methanol: 0.1 G/ml, Clear
• 敏感性常温常压下稳定，避免氧化物接触
• 外观形态类白色固体
• 储存条件存储低于 +30°C.
• 产品应用该化合物用于制备DNA结合的硝酸银综合体. 苯二-丙烯丁二氨基苯基苯丙胺是ACHE抑制剂PALLIDOXIME(P701120)的N-甲基类似物.
• 性质描述熔点110-113°C乙醇溶解度:0.1g/mL,清沏.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(经口)
  水生慢性毒性 类别3
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  严重眼损伤 类别1
• 警示词Warning(警告)
• 危险描述H302 |吞咽有害.
  H412 |对水生生物有害并具有长期持续影响.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H318 |造成严重眼损伤.
• 防范说明P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378
• 危险等级4.1
• UN编号1325.0
• 危险品标志Xn,Xi
• 风险等级Irritant
• 包装等级Ⅱ
• 安全声明26-36/37/39-37/39
• 危险类别码22-37/38-41-36/37/38-20/22
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 1121-60-4 = 873-69-8
  反应条件:1.1 Reagents: Sodium Acetate,Hydroxyamine Hydrochloride Solvents: Ethanol; 2 H,60 °C
  标题:Design,Synthesis,Biological Evaluation And Molecular Docking Studies Of Phenylpropanoid Derivatives As Potent Anti-Hepatitis B Virus Agents
  作者:Liu,Sheng; Et Al
  参考文献:European Journal Of Medicinal Chemistry 日期:2015 卷标:95 页码:473-482]
  
  109-06-8 = 873-69-8
  反应条件:1.1 Reagents: Tert-Butyl Nitrite Catalysts: Cupric Acetate,N-Hydroxyphthalimide Solvents: Acetonitrile; 24 H,80 °C
  标题:Copper(Ii)-Promoted Direct Conversion Of Methylarenes Into Aromatic Oximes
  作者:Yu,Jiatao; Et Al
  参考文献:Organic & Biomolecular Chemistry 日期:2015 卷标:13(27) 页码:7397-7401]
  
  1758-54-9 = 873-69-8
  反应条件:1.1 Reagents: Sodium Ethoxide,Hydroxyamine Hydrochloride Solvents: Ethanol
  标题:2-Pyridyl Ketone Oximes In Iron(Iii) Carboxylate Chemistry: Synthesis,Structural And Physical Studies Of Tetranuclear Clusters Containing The [fe4(μ3-O)2]8+ 'Butterfly' Core
  作者:Gkioni,Catherine; Et Al
  参考文献:Polyhedron 日期:2009 卷标:28(15) 页码:3221-3226]
  
  72196-03-3 = 873-69-8
  反应条件:1.1 Reagents: Water Solvents: Water
  标题:Preparation Of Bis(Quaternary Pyridinium Aldoximes)
  作者:Joshi,H. C.; Et Al
  参考文献:Indian Journal Of Chemistry 日期:1979 卷标:(2) 页码:162-3]
  
  72196-04-4 = 873-69-8
  反应条件:1.1 Reagents: Water Solvents: Water
  标题:Preparation Of Bis(Quaternary Pyridinium Aldoximes)
  作者:Joshi,H. C.; Et Al
  参考文献:Indian Journal Of Chemistry 日期:1979 卷标:(2) 页码:162-3]
  
  106-91-2 = 873-69-8
  反应条件:1.1 Solvents: Tetrahydrofuran; 24 H,70 °C2.1 Catalysts: Calcium Chloride Solvents: Dimethylformamide; 30 Min,Rt2.2 Reagents: Potassium Carbonate; 1 H,Rt2.3 Solvents: Dimethylformamide; 1 H,Rt; 24 H,Rt
  标题:Chemical Modification Of Glycidyl Methacrylate Copolymers With Oximes Containing Pyridine Groups
  作者:Sattarzadeh,Sahar; Et Al
  参考文献:Pharma Chemica 日期:2012 卷标:4(6) 页码:2340-2346]
  
  65321-24-6 = 873-69-8 + 5424-19-1 + 100-70-9 + 71-50-1
  反应条件:1.1 Solvents: Water
  标题:Studies On The Decomposition Of Hgg 12 In Aqueous Solution
  作者:Eyer,Peter; Et Al
  参考文献:Archiv Der Pharmazie (Weinheim 日期:1986 卷标:319(6) 页码:558-66]
  
  873-69-8 = 873-69-8
  反应条件:1.1 Solvents: Ethanol; 2 H,60 °C
  标题:Synthesis And Anti Pseudomonas Aeruginosa Activity Of Metal Complexes Of Oxime,Semicarbazone And Phenylhydrazone
  作者:Hania,Majed M.
  参考文献:Material Science Research India 日期:2006 卷标:3 页码:59-62]
  
  3731-51-9 = 873-69-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Aldoxime,1,3,5-Trihydroxy-1,3,5-Triazine-2,4,6(1H,3H,5H)-Trione Solvents: Water; 42 H,100 °C
  标题:Metal-Free: A Novel And Efficient Aerobic Oxidation Of Primary Amines To Oximes Using N,N',N''-Trihydroxyisocyanuric Acid And Acetaldoxime As Catalysts In Water
  作者:Yu,Jiatao; Et Al
  参考文献:Synlett 日期:2014 卷标:25(13) 页码:1873-1878]
  
  3731-51-9 = 873-69-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Aldoxime,Tempo,Indium Trichloride Solvents: Toluene; 8 H,100 °C
  标题:A Novel And Efficient Catalytic System Including Tempo/acetaldoxime/incl3 For Aerobic Oxidation Of Primary Amines To Oximes
  作者:Yu,Jiatao; Et Al
  参考文献:Tetrahedron Letters 日期:2014 卷标:55(42) 页码:5751-5755]
  
  586-98-1 = 873-69-8
  反应条件:1.1 Reagents: Hydrogen Peroxide,Hydroxylamine Catalysts: 2597233-34-4 Solvents: Acetonitrile,Water; 20 Min,Rt; 2 H,Rt -> 70 °C
  标题:Dioxido-Vanadium(V) Complex Catalyzed Oxidation Of Alcohols And Tandem Synthesis Of Oximes: A Simple Catalytic Protocol For C-N Bond Formation
  作者:Kurbah,Sunshine Dominic
  参考文献:Journal Of Coordination Chemistry 日期:2021 卷标:74(4-6) 页码:905-918]
  
  873-69-8 + 106-91-2 = 873-69-8
  反应条件:1.1 Catalysts: Calcium Chloride Solvents: Dimethylformamide; 30 Min,Rt1.2 Reagents: Potassium Carbonate; 1 H,Rt1.3 Solvents: Dimethylformamide; 1 H,Rt; 24 H,Rt
  标题:Chemical Modification Of Glycidyl Methacrylate Copolymers With Oximes Containing Pyridine Groups
  作者:Sattarzadeh,Sahar; Et Al
  参考文献:Pharma Chemica 日期:2012 卷标:4(6) 页码:2340-2346]
  
  65321-24-6 = 873-69-8 [标题:Reaction Conditions
  标题:Chemical Stability Of The Hagedorn Oximes Hgg-12 And Hi-6
  作者:Eyer,Peter; Et Al
  参考文献:Archiv Der Pharmazie (Weinheim 日期:1985 卷标:318(10) 页码:938-46]
  
  72196-00-0 = 873-69-8
  反应条件:1.1 Reagents: Water Solvents: Water
  标题:Preparation Of Bis(Quaternary Pyridinium Aldoximes)
  作者:Joshi,H. C.; Et Al
  参考文献:Indian Journal Of Chemistry 日期:1979 卷标:(2) 页码:162-3]
  
  873-69-8 = 873-69-8
  反应条件:1.1 Reagents: Silica,Thionyl Chloride; 48 H,Reflux1.2 Solvents: Ethyl Acetate; 48 H,Rt
  标题:Copper Complex Anchored On Sba-15 Matrix: An Efficient Catalyst In Green Synthesis Of Pyran-Annulated Spirooxindoles In Aqueous Medium
  作者:Ghorbani,Sayedhosein; Et Al
  参考文献:Journal Of Chemical 日期:2015 卷标:5(3) 页码:2762-2772]
  
  98-98-6 = 873-69-8
  反应条件:1.1 Reagents: Pyridine,Hydroxyamine Hydrochloride Solvents: Ethanol; Rt
  标题:Laccase-Catalysed Biotransformation Of Collismycin Derivatives. A Novel Enzymatic Approach For The Cleavage Of Oximes
  作者:Gonzalez-Sabin,Javier; Et Al
  参考文献:Green Chemistry 日期:2016 卷标:18(4) 页码:989-994]
  
  1121-60-4 = 873-69-8
  反应条件:1.1 Reagents: Sodium Acetate,Hydroxyamine Hydrochloride Solvents: Ethanol,Water; 10 Min,80 - 90 °C2.1 Solvents: Ethanol; 2 H,60 °C
  标题:Synthesis And Anti Pseudomonas Aeruginosa Activity Of Metal Complexes Of Oxime,Semicarbazone And Phenylhydrazone
  作者:Hania,Majed M.
  参考文献:Material Science Research India 日期:2006 卷标:3 页码:59-62

海关参考信息

• 2933310010-吡啶
  2939800000-其他生物碱
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 防范代码详解
• ➥ 危险代码说明
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• ➥ REACH监管