CAS: 1120-16-7; Dodecanamide

该化合物是在室温下白到非白固态的外表,由于长期的碳氢化合物链,熔点相对较高.Dodeanaminide在乙醇和氯仿等有机溶剂中溶解,但水溶性有限,反映了其疏水性.这种复合物展示表面活性特性,使其在各种应用中有用,包括乳化剂,润滑剂和个人护理产品的配制.此外,Dodeanaminide可以参与氨化物典型的化学反应,例如水解和恐吓.在正常条件下的稳定性和形成氢结的能力有助于其在工业应用中的效用.安全数据表明,虽然它可能在与皮肤或眼睛接触时引起刺激,但一般认为它具有低毒性.建议在与该物质打交道时采取适当处理和安全防范措施.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号2437-25-4 十二腈 | CAS号112-54-9 十二醛 | CAS号13372-76-4 (NE)-N-dodecyli... | CAS号143-07-7 月桂酸 | CAS号43009-32-1 β-Chlor-pivalophenon | CAS号112-55-0 十二硫醇 | CAS号112-16-3 十二酰氯 | CAS号106-33-2 月桂酸乙酯 | CAS号2437-23-2 ammonium laurate | CAS号7596-88-5 N-月桂酰甘氨酸 | CAS号3775-51-7 月桂酰基二乙酸基胺 | CAS号3007-31-6 双十二烷基胺 | CAS号124-22-1 十二胺 | CAS号54574-77-5 N-dodecyl-4-met... | CAS号33422-43-4 N-dodecyldodeca... | CAS号143-07-7 月桂酸 | CAS号7664-41-7 氨 | CAS号2437-25-4 十二腈 | CAS号7307-55-3 正十一胺

合成工艺路线路线简述

  • 合成目标产物 Dodecanamide 主要起始原料 Dodecanenitrile
  • (文献来源)合成步骤主要原料 Dodecanenitrile
十二腈置于乙醛肟,Copper(II) Chloride Dihydrate体系中,用 水 用作溶剂,化学反应 12.0H,以90%的收率获得月桂酰胺
参考文献:乙醛肟在铜(II)催化的腈水合反应中
标题:乙醛肟在铜(II)催化的腈水合反应中
摘要:描述了一种通过在环境友好的水中使用廉价的铜盐催化剂和可商购的乙醛肟将腈选择性水合为酰胺的有效方法.根据该方案,包括芳族腈,杂环腈和脂族腈的腈以非常好或优异的收率转化为相应的酰胺.
Doi:10.1016/j.Tetlet.2011.11.075

海关参考信息

专利信息


专利号:US-4720573-A
优先权日:1986-07-31
标 题:Process for synthesis of glutamic acid from acrylate, amide and synthesis gas
发明人:LIN JIANG-JEN
权利人:TEXACO INC
摘要:A process for the synthesis of glutamic acid intermediate from an acrylate, amide and syngas by reacting them in the presence of a catalyst comprising a cobalt-containing compound, a bis-phosphine ligand and a solvent at a pressure of at least 500 psi and a temperature of at least 50° C. and thereafter extracting the glutamic acid.

专利号:US-12208146-B2
优先权日:2018-11-19
标 题 :Reconstituted HDL nanoparticles for delivery of radioactive agents and uses thereof
发明人:LACKO ANDRAS G; PROKAI LASZLO; ISAAC-OLIVÉ KEILA
权利人:UNIV OF NORTH TEXAS HEALTH SCIENCE CENTER; THE AUTONOMOUS UNIV OF THE STATE OF MEXICO
摘要:Despite the widespread use of nanotechnology in radio-imaging applications, lipoprotein based delivery systems received only limited attention so far. The subject application provides for the synthesis of a novel hydrophobic radio-imaging tracer. This tracer, comprising a hydrazinonicotinic acid (HYNIC)-N-dodecylamide and 99mTc conjugate can be encapsulated into rHDL nanoparticles (NPs). These rHDL NPs can selectively target the Scavenger Receptor type B1 (SR-B1) that is overexpressed on most cancer cells due to excess demand for cholesterol for membrane biogenesis and thus can target tumors in-vivo. Details of the tracer synthesis, characterization of rHDL/tracer complex, in-vitro uptake, stability studies and in-vivo application of this new radio-imaging approach are provided.

专利号:US-5780658-A
优先权日:1995-01-10
标 题 :Process for the synthesis of cationic surfactants comprising esterification with basic character amino acids
发明人:MARTINEZ-PARDO MARTA ROSA INFA; MESTRES AUGUSTIN CONTIJOCH; SERRABASA PILAR ERRA
权利人:MIRET LAB
摘要:The process of the invention is directed to the synthesis of cationic type surfactant compounds consisting of natural basic-character amino acids, and any of their homologs, suitably modified for the purpose of obtaining products having specific applications as antimicrobial (biocidal) agents. The process comprises a first step of esterification of an amino acid, and a second step of the condensation of a fatty acid chloride with an esterified amino acid derivative. Nontoxic reaction media and catalysts are used, and a final product free from impurities is obtained. The cost of the process of the invention is reduced from prior art processes due to the use of cheaper starting materials and simpler equipment.

专利号:US-5681971-A
优先权日:1994-12-12
标题 :Synthesis of fatty N-alkyl amides
发明人:SCHEIBEL JEFFREY JOHN; SHUMATE ROBERT EDWARD
权利人:PROCTER & GAMBLE
摘要:Fatty N-alkyl amides are synthesized directly from glycerides (preferably triglycerides) and amines in the absence of a catalyst, and preferably without a solvent. The method provides for products suitable for use without further purification, preferably after separating the glycerol and amide products. The disclosed method is also useful for the synthesis of glycerol from glycerides and ammonia and/or primary amines.

专利号:US-5097065-A
优先权日:1985-04-05
标题:Process for synthesis of a novel amino acid from styrene, acetamide and syngas
发明人:LIN JIANG-JEN
权利人:TEXACO INC
摘要:A phenyl substituted amino acid derivative is synthesized by reacting styrene, acetamide and synthesis gas with a bimetallic catalyst comprising a rhodium-containing compound and a cobalt-containing compound, optionally in the presence of a solvent at a pressure of at least 500 psi and a temperature of at least 50° C. The novel amino acid contains a carboxylic acid group, an acetamido group at the alpha-position and a phenyl group at the beta-position.

专利号:US-4892687-A
优先权日:1986-10-08
标题:Process for synthesis of amidoacids using a cobalt catalyst and a bidental phosphine ligand
发明人:LIN JIANG-JEN
权利人:TEXACO INC
摘要:A process is disclosed for producing N-acetyl-aminoacid which comprises reacting a feedstock from the group consisting of simple olefins, acetamide and synthesis gas with a catalyst comprising a cobalt-containing compound promoted by a bidental-phosphine ligand in a solvent at a pressure of 500 psi or greater and a temperature of 50 DEG C. or greater. The presence of the ligand increases both reaction rate and cobalt catalyst stability.
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参考文献:10.1007/s12602-011-9068-5
摘要:Turovskiy Y, Chikindas ML. Zinc Lactate and Sapindin Act Synergistically with Lactocin 160 Against Gardnerella vaginalis. Probiotics and Antimicrobial Proteins. 2011 Mar 19;3(2):144. doi: 10.1007/s12602-011-9068-5.
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