CAS: 38191-34-3; 2-Amino-5-Bromophenol

上下游产品

6-bromobenzo[d]oxazol-2(3H)-one 5-bromo-2-nitrophenol 2-amino-5-bromophenyl sulphate 1-azido-4-bromobenzene 5-bromo-2-iodo-phenol 1-benzoylamino-2-benzoyloxy-4-bromo-benzene 4-bromo-2-hydroxy-benzenediazonium betaine N-(4-bromo-2-hydroxy-phenyl)-N'-(3,4-dichloro-phenyl)-ureaN-(4-bromo-2-hydroxy-phenyl)-N'-(3,4-dichloro-phenyl)-urea

间溴苯酚置于sodium Nitrate,硫酸,Tin(Ll) Chloride体系中,用 乙醇,二氯甲烷,水 用作溶剂,化学反应 10.0H,反应生成2-氨基-5-溴苯酚
参考文献:用于有机白光发光二极管和固态照明的高效tris(8-羟基喹啉)铝(alq3)配合物
标题:用于有机白光发光二极管和固态照明的高效tris(8-羟基喹啉)铝(alq3)配合物
摘要:三(8-羟基喹啉)铝(alq 3)配合物的8-羟基喹啉配体上的吸电子和供电子取代基的组合可控制homo和lumo能量以及负责从该配合物中发射的homo-Lumo间隙.在这里,我们提出了一个系统的研究,以调节alq 3配合物从绿色到蓝色区域的发射和电致发光(el).在这项研究中,我们探索了c4和c6上给电子取代基的组合.化合物1-6显示0.15和0.57之间478和526纳米,和荧光量子产率之间的发射调谐.化合物2-6用作有机发光二极管(oled)的发射器和主体.观测到的最高oled外部量子效率(eqe)为4.6%,在alq 3配合物中观测到的最高.另外,化合物3-5被用作红色磷光掺杂剂,以获得白色发光二极管(woled)的主机.Woled显示出高效率(eqe高达19%)和高白色纯度(显色指数(cri~85).
Doi:10.1002/chem.201100707

专利信息

专利号:WO-2023072966-A1
优先权日:2021-10-26
标题:Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
发明人：DEAU EMMANUEL; GEORGE PASCAL; MEIJER LAURENT; MIEGE FRÉDÉRIC
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) wherein R 1 represents a (C 4 -C 6) alkyl group, a (C 3 -C 8) cycloalkyl group, a bridged (C 6 -C 10 )cycloalkyl group, a fused phenyl group, a substituted phenyl group, a R'-L- group, wherein L is either a single bond or a (C 1 -C 3 )alkanediyl group, and R' represents, a (C 3 -C 8 )heterocycloalkyl group, or a (C 3 -C 8 )heteroaryl group, or a R''-L- group wherein L is a (C 1 -C 3 )alkanediyl group, and R'' is an optionally substituted phenyl group; R 2 is selected from the group consisting of a hydrogen atom and a (C 1 -C 3 )alkyl group; R 5 represents a hydrogen atom, a (C 1 -C 4 )alkyl group or a (C 3 -C 6 )cycloalkyl group or any of its pharmaceutically acceptable salt. The present invention further relates to a composition comprising a compound of formula (I) and a process for manufacturing said compound as well as its synthesis intermediates. It also relates to said compound for use as a medicament, in particular in the treatment and/or prevention of cognitive deficits and neuroinflammation associated with Down syndrome; Alzheimer's disease; dementia; tauopathies; Parkinson's disease; CDKL5 Deficiency Disorder; Phelan-McDermid syndrome; autism; type 1 and type 2 diabetes; abnormal folate and methionine metabolism; osteoarthritis and tendinopathy; Duchenne muscular dystrophy; cancers and leukemias; neuroinflammation, anemia, infections caused by unicellular parasites, viral infections and for regulating body temperature.

专利号:US-11020399-B2
优先权日:2011-05-04
标 题:Intermediates useful in the synthesis of compounds as modulators of protein kinases

专利号:US-9604966-B2
优先权日:2013-02-16
标 题 :Crizotinib preparation method
发明人：LI YUANQIANG; QIAN JIANQIANG; CHE DAQING
权利人:ZHEJIANG JIUZHOU PHARM CO LTD; ZHEJIANG JIUZHOU PHARM CO LTD
摘要:The present invention relates to the technical field of medicine and organic synthesis, particularly to a method for preparing crizotinib. The method comprises the compound of formula b and the compound of formula e undergoing Suzuki coupling reaction to produce the compound of formula a which then was subjected to deprotection to afford (±) crizotinib.

专利号:CN-119241459-A
优先权日:2024-09-03
标题:Benzo (A) benzo (B) benzo (A oxazole/benzo Synthesis method of thiazole compound