专利号:US-4713383-A 优先权日:1984-10-01 标 题:Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses 发明人:FRANCIS JOHN E; GELOTTE KARL O 权利人:CIBA GEIGY CORP 摘要:[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N-R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N-R3.
专利号:NO-344857-B1 优先权日:2004-02-13 标题:Contrast agents, precursor compounds thereof, preparations containing them, methods of synthesis and their use in imaging
摘要:Kikelj, D., Science of Synthesis, (2004) 16, 597. 摘要:Kikelj, D., Science of Synthesis, (2004) 16, 637. 摘要:Collier, S. J.; Langer, P., Science of Synthesis, (2004) 19, 403.