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CAS号95-53-4 邻甲苯胺 | CAS号95-70-5 2,5-二氨基甲苯 | CAS号3029-60-5 2,5-Cyclohexadi... | CAS号6406-71-9 4-methyl-N1-phe... | CAS号4661-54-5 8-imino-3,7-dim...

邻甲苯胺置于亚硝酸体系中,化学反应生成 碱性红 2
参考文献:Jaubert,Chemische Berichte,1895,Vol. 28,P. 273
标题:Jaubert,Chemische Berichte,1895,Vol. 28,P. 273

专利信息

专利号:US-12018313-B2
优先权日:2016-12-28
标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles
发明人：EMBREE MALLORY
权利人:NATIVE MICROBIALS INC
摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.

专利号:US-12275733-B2
优先权日:2016-11-07
标 题:Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
发明人：GRETZKE DIRK; RITZELER OLAF; HEINELT UWE; WEHNER VOLKMAR; SCHMIDT FRIEDEMANN
权利人:SANOFI SA
摘要:The present invention relates to 8-aryl-substituted and 8-heteroaryl-substituted 9H-pyrido[3,4-b]indoles of the formula (I), in which A, E, G, R1 to R6 and R10 are as defined in the claims, which stimulate chondrogenesis and cartilage matrix synthesis and can be used in the treatment of cartilage disorders and conditions in which a regeneration of damaged cartilage is desired, for example joint diseases such as osteoarthritis. The invention furthermore relates to processes for the synthesis of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.

专利号:WO-2021148064-A1
优先权日:2020-01-22
标 题 :Biodegradable polyurethane foam, biodegradable polyurethane foam-based material for saccharide-cleaving enzyme production, method of synthesis and use thereof
发明人：BENES HYNEK; BUJOK SONIA; PARUZEL ALEKSANDRA; ZAJICOVA VERONIKA; HNATKOVA TEREZA; BUSSCHER GUUSKE FREDERIKE; SCHMEETS ALEX ALOIS JOSEPH
权利人:USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I; BIOMOSAE
摘要:The present invention relates to a method of synthesis of a biodegradable polyurethane foam, comprising the following steps: i) mixing of at least one aliphatic isocyanate bearing at least two isocyanate groups with at least one saccharide in weight ratio of from 1:1 to 30:1 to form a saccharide-isocyanate precursor; ii) homogenization of the saccharide-isocyanate precursor from step i) with 20 to 70 % (w/w) of at least one biodegradable aliphatic polyester-ether polyol having molecular mass in the range of from 0 to 10 000 g/mol and hydroxyl number from 10 to 100 mgKOH/g, 1 to 5 % (w/w) of water, and 1 to 10 % (w/w) of at least one blowing agent other than water, related to the total weight of the resulting mixture; iii) foaming of the homogenized mixture from step ii) at the temperature of from 20 to 100 °C, resulting in the biodegradable polyurethane foam comprising incorporated saccharide. The invention further relates to a biodegradable polyurethane foam obtainable by this method, to a biodegradable polyurethane foam-based material for saccharide-cleaving enzyme production and to the use thereof.

专利号:US-7132098-B2
优先权日:1998-10-06
标题 :Method for the treatment of chemonucleolysis
发明人：MASUDA KOICHI; THONAR EUGENE J-M A; AN HOWARD
权利人:MASUDA KOICHI; THONAR EUGENE J-M A; AN HOWARD
摘要:The invention relates to a method of treatment for a mammal in need of chemonucleolysis. The method comprising the administration of an effective proteoglycan cleaving amount of a proteoglycan-degrading enzyme and an effective amount of a growth factor effective in promoting the synthesis of a matrix component. The proteoglycan-degrading enzyme is preferably chondroitinase. The growth factor is preferably osteogenic protein. The proteoglycan-degrading enzyme and the growth factor are preferably administered simultaneously.

专利号:US-8754206-B2
优先权日:2011-06-21
标 题 :Metal (III) complex of biuret-amide based macrocyclic ligand as green oxidation catalyst
发明人：SENGUPTA SAYAM; PANDA CHAKADOLA; GHOSH MUNMUN
权利人:SENGUPTA SAYAM; PANDA CHAKADOLA; GHOSH MUNMUN; COUNCIL SCIENT IND RES
摘要:The present invention discloses metal (III) complex of a biuret-amide based macrocyclic ligand as green catalysts that exhibit both excellent reactivity for the activation of H 2 O 2 and high stability at low pH and high ionic strength. The invention also provides macrocyclic biuret amide based ligand for designing of functional peroxidase mimics. Further, the present invention discloses synthesis of said metal (III) complex of a biuret-amide based macrocyclic ligand.

专利号:WO-2011000481-A1
优先权日:2009-07-02
标 题 :Synthesis of pyrazine derivates
发明人：IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
权利人:MERCK PATENT GMBH; IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
摘要:The present invention relates to a method for producing pyrazine derivates, wherein the reaction medium comprises at least one ionic liquid, and to the use of ionic liquids for producing pyrazine derivates.