CAS: 518-82-1; 1,3,8-Trihydroxy-6-Methylanthracene-9,10-Dione

上下游产品

CAS号6030-60-0 (3,8-diacetylox... | CAS号5018-84-8 1-hydroxy-6,8-d... | CAS号14787-38-3 7-甲基-5-羟基萘醌 | CAS号491-60-1 大黄素蒽酮 | CAS号541-47-9 3,3-二甲基丙烯酸 | CAS号25436-25-3 3,3-二甲基丙烯酸三甲基硅酯 | CAS号76695-92-6 5-hydroxy-7-met... | CAS号76695-89-1 7-methyl-5-((tr... | CAS号106-51-4 苯醌 | CAS号548-03-8 原金丝桃素 | CAS号491-60-1 大黄素蒽酮 | CAS号481-74-3 大黄酚 | CAS号613-12-7 2-甲基蒽 | CAS号521-61-9 大黄素甲醚 | CAS号3775-08-4 1-O-Methylemodin | CAS号3774-64-9 大黄素-8-甲醚 | CAS号84993-87-3 [4,5-diacetylox... | CAS号476-46-0 链蠕孢素 | CAS号5018-84-8 1-hydroxy-6,8-d...

双醋瑞因杂质8置于sodium Hydroxide体系中,化学反应 2.0H,以100%的收率获得产物大黄素
参考文献:高比放射性[3H]大黄素的合成
标题:高比放射性[3H]大黄素的合成
摘要:大黄素是 Pyrenochaeta Terrestris 生物合成 Cynodontin 中大黄酚的前体,已通过溴甲基大黄素的氢解以高比放射性 (12.5 Ci/mmol) 氚化.
DOI:10.1002/jlcr.2580360811

专利信息

专利号:US-6531591-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:EP-1202998-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:US-2022378721-A1
优先权日:2019-10-24
标 题 :Protein kinase inhibitors and use thereof for treatment of neurodegenerative diseases
发明人：SRIDHAR JAYALAKSHMI; BRATTON MELYSSA; GOYAL NAVNEET; JHA VISHWAJEET; SCHROEDER RICHARD
权利人:XAVIER UNIV OF LOUISIANA
摘要:The present disclosure relates to compounds that act as protein kinase inhibitors, especially CK1δ and/or CK1ε inhibitors, which can be used to treat a serine threonine kinase-dependent disease and condition, such as neurodegenerative diseases like Alzheimer's Disease, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for neurodegenerative diseases, including Alzheimer's disease.

专利号:WO-2007094533-A1
优先权日:2006-02-17
标题:Composition for inhibiting collagen degradation and promoting collagen synthesis comprising emodin
发明人：PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK
权利人:BIOSPECTRUM INC; PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK
摘要:Disclosed is a composition, comprising emodin, for inhibiting collagen degradation and promoting collagen synthesis. The composition stimulates cell regeneration by promoting the synthesis of collagen by normal fibroblasts, alleviates wrinkles, and imparts the skin with elasticity. Also, the composition can be used as a preparation for external use for skin, such as cosmetics.

专利号:US-8133913-B2
优先权日:2006-10-04
标 题 :Substituted indeno [1,2-b]indole derivatives as novel inhibitors of protein kinase CK2 and their use as tumor therapeutic agents, cytostatics and diagnostic aids
发明人：HEMMERLING HANS-JORG; GOTZ CLAUDIA; JOSE JOACHIM
权利人:HEMMERLING HANS-JORG; GOTZ CLAUDIA; JOSE JOACHIM; UNIV DUESSELDORF H HEINE
摘要:Synthesis of novel substituted indeno[1,2-b]indole derivatives of the type of 5,6,7,8-tetrahydroindeno[1,2-b]indole-9,10-diones and 5H-indeno[1,2-b]indole-6,9,10-triones, which show pronounced inhibition of the human protein kinase CK2, and the use thereof as active ingredients in medicaments and/or drug products in particular for the treatment of neoplastic diseases.

专利号:US-12187735-B2
优先权日:2018-09-17
标 题:Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease
发明人：LING XIANG; LI QINGYONG; LI FENGZHI
权利人:CANGET BIOTEKPHARMA LLC
摘要:Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.