CAS: 700-96-9; 3,4-Dimethoxythiophenol

上下游产品

1,2-dimethoxybenzene 3,4-dimethoxyaniline N-(3,4-dimethoxyphenylthiomethyl)benzamide 4-Bromoveratrole 4-butylsulfanyl-1,2-dimethoxy-benzene 4-[(3,4-dimethoxy-phenylsulfanyl)-carboximidoyl]-benzoic acid ethyl ester N-(3,4-dimethoxyphenylthiomethyl)benzamide 4-methoxy-benzoic acid-{[(3,4-dimethoxy-phenylsulfanyl)-methyl]-amide}

3,4-二甲氧基苯磺酰氯置于磷化氢体系中,化学反应生成 3,4-二甲氧基苯硫酚
参考文献:Potential Metabolites Of Tricyclic Neuroleptics: 3,7-Dimethoxy And 7,8-Dimethoxy Derivatives Of 10-(4-Methylpiperazino)-10,11-Dihydrodibenzo[b,F]Thiepin
标题:Potential Metabolites Of Tricyclic Neuroleptics: 3,7-Dimethoxy And 7,8-Dimethoxy Derivatives Of 10-(4-Methylpiperazino)-10,11-Dihydrodibenzo[b,F]Thiepin
摘要:2-碘-4-甲氧基苯甲酸与3-甲氧基噻吩酚反应反应生成酸ii,经过醇iii和腈iv转化为[4-甲氧基-2-(3-甲氧基苯硫基)苯基]乙酸(V).2-碘苯乙酸与3,4-二甲氧基噻吩酚反应得到异构体[2-(3,4-二甲氧基苯硫基)苯基]乙酸(Xi).酸v和酸xi通过环化得到酮via和vib,经过与1-甲基哌嗪和四氯化钛反应转化为烯胺ixa和ixb.用二硼烷还原这些烯胺得到标题化合物.尝试用乙酸中的锌还原这些烯胺导致氢解,主要产物为2,3-二甲氧基和3,7-二甲氧基-10,11-二氢二苯并[b,F]噻吩(Xab).
DOI:10.1135/cccc19811808

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-9481645-B2
优先权日:2014-02-21
标 题:Composition, synthesis, and use of a new class of isonitriles
发明人：FLEMING FRASER FERGUSSON; LUJAN-MONTELONGO JESUS ARMANDO
权利人:DUQUESNE UNIV OF THE HOLY GHOST
摘要:This invention relates to novel isonitriles, including arylthio isonitriles, and methods for their preparation. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.

专利号:UA-71917-C2
优先权日:1998-06-24
标题:A PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE OF a, b- UNSATURATED ALKENOATE RESIN

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.