CAS: 140-39-6; P-Tolyl Acetate

该化合物是一种有机化合物,其特性为酯性功能组,源自p-toluidine和乙酸酸的反应;该化合物一般是一种无色的淡黄色液体,具有甜甜果味,在香味和口味行业有用;其分子配方为C9H10O2, 其温和沸点和密度,在酯类中很常见.4-Mecybly苯乙酸乙酸乙酯的溶性在有机溶剂中是已知的,而在水中溶性较低,但通常用作溶剂和其他化学化合物的合成.此外,该化合物可能具有低毒性,但在处理时,应像处理许多有机溶剂一样采取安全防范措施.其应用范围扩大到香水,调味和有机合成的中间体.

结构式图片

相似化合物

3245-23-6 878-00-2 2628-16-2

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

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CAS号106-44-5 对甲酚 | CAS号108-24-7 乙酸酐 | CAS号75-36-5 乙酰氯 | CAS号64-19-7 冰醋酸 | CAS号506-96-7 乙酰溴 | CAS号834-25-3 Benzene,1-methy... | CAS号122-00-9 对甲基苯乙酮 | CAS号104-93-8 4-甲基苯甲醚(MSO) | CAS号61599-05-1 4-acetyl-4-meth... | CAS号10557-67-2 N-(4-methylphen... | CAS号106149-34-2 1-(2-hydroxy-5-... | CAS号51069-84-2 4-氯-3-甲酰基-6-甲基香豆素 | CAS号42059-81-4 3-甲酰基-6-甲基色酮 | CAS号93-92-5 乙酸苏合香酯 | CAS号4030-18-6 1-乙酰基吡咯烷 | CAS号106-44-5 对甲酚 | CAS号16714-41-3 tetrakis(4-meth... | CAS号75-36-5 乙酰氯 | CAS号875-59-2 4'-羟基-2'-甲基苯乙酮 | CAS号2345-34-8 4-乙酰氧基苯甲酸

合成工艺路线路线简述

    对甲酚置于吡啶,乙酸酐体系中,化学反应生成乙酸对甲酚酯
    参考文献:Substantially Linear Monomeric Composition And Liquid Crystal Polymeric
    标题:Substantially Linear Monomeric Composition And Liquid Crystal Polymeric
    摘要:本文描述了一种新颖的基本线性单体组合物,可以与一个或多个双官能基单体聚合,从而得到具有液晶性能的新型聚合物组合物.本发明还涉及一种制备这种新型基本线性单体组合物的方法.

    海关参考信息

    专利信息


    专利号:US-11999757-B2
    优先权日:2017-11-01
    标 题:Synthesis of boronate ester derivatives and uses thereof
    发明人:BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
    权利人:MELINTA SUBSIDIARY CORP
    摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

    专利号:US-10669292-B2
    优先权日:2014-05-05
    标 题 :Synthesis of boronate salts and uses thereof
    发明人:HECKER SCOTT; BOYER SERGE
    权利人:REMPEX PHARMACEUTICALS INC
    摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

    专利号:US-11306041-B2
    优先权日:2017-03-30
    标 题:Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts
    发明人:SCHINSKI WILLIAM; GOLDMAN ALAN; GUNNOE THOMAS B; WEBSTER-GARDINER MICHAEL S; SCHWARTZ NICHOLE
    权利人:UNIV VIRGINIA PATENT FOUNDATION
    摘要:Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN).

    专利号:US-9315483-B2
    优先权日:2007-09-13
    标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
    发明人:JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
    权利人:CONCERT PHARMACEUTICALS INC
    摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

    专利号:US-9428524-B2
    优先权日:2010-05-25
    标 题:Synthetic process for the manufacture of ecteinascidin compounds
    发明人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN
    权利人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN; PHARMA MAR SA
    摘要:This invention relates to compounds of formula II: wherein R 1 , R 2 , Prot SH , and Prot NH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.

    专利号:US-6951878-B2
    优先权日:1998-03-12
    标 题:Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases)
    发明人:MOELLER NIELS PETER HUNDAHL; ANDERSEN HENRIK SUNE; IVERSEN LARS FOGH; OLSEN OLE HVILSTED; BRANNER SVEN; HOLSWORTH DANIEL DALE; BAKIR FARID; JUDGE LUKE MILBURN; AXE FRANK URBAN; JONES TODD KEVIN; RIPKA WILLIAM CHARLES; GE YU; UYEDA ROY TERUYUKI
    权利人:NOVO NORDISK AS
    摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. n The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.
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    主要参考文献

    [参考文献]: Alfonso Pérez-Garrido, Et Al. Convenient Qsar Model For Predicting The Complexation Of Structurally Diverse Compounds With Beta-Cyclodextrins. Bioorg Med Chem. 2009 Jan 15;17(2):896-904.

    合成参考文献


    摘要:Chen, P.; Liu, G., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 214.
    摘要:Munz, D., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 2, 276.
    摘要:Wu, T.; Moeller, K. D., Science of Synthesis: Special Topics, (2021) 1, 490.
    摘要:Food and Cosmetics Toxicology., 12(391), 1974
    摘要:Yerien, D. E.; Barata-Vallejo, S.; Postigo, A., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 35.
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