1-[(2E)-4-Bromo-3-Methylbut-2-En-1-Yl]-1,3,5,7-Tetraazatricyclo[3.3.1.13,7]Decan-1-Ium Bromide置于盐酸,Sodium Carbonate,三乙胺,三氟乙酸,Sodium Hydroxide体系中,用 甲醇,乙醇,二氯甲烷,水,乙酸乙酯,正丁醇 用作溶剂,化学反应 14.0H,反应生成玉米素 参考文献:Large-Scale Synthesis Of (E)-4-Amino-2-Methylbut-2-En-1-Ol: Key Building Block For The Synthesis Of Trans-Zeatin 标题:Large-Scale Synthesis Of (E)-4-Amino-2-Methylbut-2-En-1-Ol: Key Building Block For The Synthesis Of Trans-Zeatin 摘要:在本文中,披露了(E)-4-氨基-2-甲基丁-2-烯-1-醇的大规模合成,Trans-扎伊丁也可以在工业规模上获得. Doi:10.14233/ajchem.2014.17644
专利号:US-2024110196-A1 优先权日:2022-08-29 标题 :Use of multigene stacking method in synthesis of nervonic acid in brassica napus 发明人:LIU FANG; WANG PANDI; WU GANG; XIONG XIAOJUAN 权利人:OIL CROPS RES INSTITUTE CAAS 摘要:The present disclosure relates to use of a multigene stacking method in synthesis of nervonic acid in Brassica napus. The present disclosure provides a multigene co-expression plant vector, including an initial backbone of pBWA(V)BII and multiple exogenous gene expression cassettes. The present disclosure further provides two plant vectors applicable to genetic transformation, including a three-gene co-expression plant vector and a five-gene co-expression plant vector. In the present disclosure, after the three-gene co-expression plant vector and the five-gene co-expression plant vector are separately transferred into the Brassica napus, the nervonic acid (NA) with a high content is synthesized in the Brassica napus through multigene co-expression. An NA ratio can be significantly increased combined with a higher seed oil content and a greater field seed yield. The plant vector realizes efficient synthesis of NA in oil crops, obtains NA-rich seed oil, and increases an added value of edible oil.
专利号:US-9943544-B2 优先权日:2015-03-18 标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer 发明人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH 权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH 摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.
专利号:US-7402418-B2 优先权日:2001-09-20 标 题:Genes participating in the synthesis of fatty acid having trans-11-,cis-13-conjugated double bond and utilization thereof 发明人:OSUMI MARI; MURASE JUNKO; IMAMURA JUN 权利人:PLANTECH RES INST; INC ADMIN AGENCY NARO 摘要:An object of the present invention is to clone a gene which is involved in synthesis of fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bone at position Δ12. The present invention provides a gene having any one of the following nucleotide sequences:n (A) a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO: 1 or 12; (B) a nucleotide sequence encoding an amino acid sequence comprising a deletion, addition or substitution of one or several amino acids with respect to the amino acid sequence shown in SEQ NO: 1 or 12, and having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; (C) a nucleotide sequence shown in SEQ ID NO: 2 or 13; (D) a nucleotide sequence comprising a deletion, addition or substitution of one or several nucleotides with respect to the nucleotide sequence shown in SEQ ID NO: 2 or 13, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; and (E) a nucleotide sequence hybridizing with the nucleotide sequence shown in SEQ ID NO: 2 or 13 or a complementary sequence thereof under stringent conditions, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12.
专利号:US-7429657-B2 优先权日:1994-11-10 标 题 :DNA molecules encoding enzymes involved in starch synthesis, vectors, bacteria, transgenic plant cells and plants containing these molecules 发明人:KOSSMANN JENS; SPRINGER FRANZISKA; ABEL GERNOT J 权利人:BAYER CROPSCIENCE AG 摘要:The present invention relates to DNA molecules encoding enzymes which are involved in the starch synthesis of plants. These enzymes represent two different isotypes of the soluble starch synthase as well as a starch granule-bound starch synthase. This invention furthermore relates to vectors, bacteria, as well as to plant cells transformed with the DNA molecules described and to plants regenerated from them. n Furthermore, the invention relates to starch that can be isolated from plants having an increased or reduced activity of the proteins described.
专利号:US-2003157592-A1 优先权日:1999-12-16 标题:Moss genes from physcomitrella patens encoding proteins involved in the synthesis of tocopherols and carotenoids 发明人:LERCHL JENS; RENZ ANDREAS; EHRHARDT THOMAS; REINDL ANDREAS; CIRPUS PETRA; BISCHOFF FRIEDRICH; FRANK MARKUS; FREUND ANNETTE; DUWENIG ELKE; SCHMIDT RALF-MICHAEL; RESKI RALF; BADUR RALF 摘要:Isolated nucleic acid molecules, designated TCMRP nucleic acid molecules, which encode novel TCMRPs from e.g. Phycomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TCMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated TCMRPs, mutated TCMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of TCMRP genes in these organisms.
专利号:WO-0112791-A1 优先权日:1999-08-12 标 题 :Dna shuffling of dioxygenase genes for production of industrial chemicals 发明人:SELIFONOV SERGEY A; NEWMAN LISA M 权利人:MAXYGEN INC; SELIFONOV SERGEY A; NEWMAN LISA M 摘要:This invention provides improved polypeptides, including dioxygenases, dehydrogenases, ligases and transferases that are useful for the biocatalytic synthesis of compounds such as α-hydroxycarboxylic acids, and aryl- and alkyl-hydroxy and carboxylic acid compounds. The polypeptides provided herein are improved in properties such as regioselectivity, enzymatic activity, stereospecificity, and the like. Methods for obtaining recombinant polynucleotides that encode these improved polypeptides are also provided, as are organisms that express the polypeptides and are thus useful for carrying out said biocatalytic syntheses. Also provided by the invention are methods for increasing said solvent resistance of organisms that are used in the synthetic methods.
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合成参考文献
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