CAS: 2537-48-6; Diethyl (Cyanomethyl)Phosphonate

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CAS号107-14-2 氯乙腈 | CAS号122-52-1 亚磷酸三乙酯 | CAS号814-49-3 氯磷酸二乙酯 | CAS号75-05-8 乙腈 | CAS号590-17-0 溴乙腈 | CAS号2213-63-0 2,3-二氯喹喔啉 | CAS号77679-10-8 diethoxyphospho... | CAS号111686-30-7 3-naphthalen-1-... | CAS号4408-78-0 膦酰基乙酸 | CAS号5299-98-9 β-亚苄基乙腈 | CAS号32444-63-6 反-4-二甲氨基肉桂腈 | CAS号33414-62-9 2-(四氢呋喃-2-基)乙腈 | CAS号4786-24-7 3-甲基巴豆腈 | CAS号4450-34-4 4-氯-3-甲基-2-丁腈 | CAS号5146-66-7 柠檬腈 | CAS号23017-29-0 Pregn-17(20)-en...

Diethyl Cyanomethylphosphonate Potassium Salt置于对硝基苯甲酸乙酯体系中,用 二甲基亚砜 用作溶剂,化学反应生成氰甲基磷酸二乙酯
参考文献:Matveeva,A. G.; Odinets,I. L.; Artyushin,O. I.,Russian Journal Of General Chemistry,1994,Vol. 64,# 12.1,P. 1735-1737
标题:Matveeva,A. G.; Odinets,I. L.; Artyushin,O. I.,Russian Journal Of General Chemistry,1994,Vol. 64,# 12.1,P. 1735-1737

专利信息

专利号:US-5442065-A
优先权日:1993-09-09
标 题:Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin
发明人：MAGNUS PHILIP D; ILIADIS THEODORE; EISENBEIS SHANE A; FAIRHURST ROBIN A
权利人:UNIV TEXAS
摘要:A process is described for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin. The synthesis allows efficient production of the enediyne as a stable, compound in good yield from the adamantyl N-protected azabicyclo[7.3.1]tridecadiyne. The adamantyl protecting group is employed in the starting material, N-adamantyl dihydroquinoline or N-adamantyl 6-methoxy quinoline. Also disclosed are process for the synthesis of 3-hydroxy-6-methoxyquinoline and several N-substituted derivatives of azobicyclo[7.3.1]tridecaenediyne. Solid tumor and leukemia assays were performed on the analogs of dynemicin. The results suggest a method that these compounds will useful in treating certain types of leukemias and solid tumors. The disclosed synthesis provides a route to new dynemicin intermediates and analogs which will allow development of second and third generation dynemicins.

专利号:US-8779121-B2
优先权日:2012-10-12
标题:Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：CARRANZA MARIA DEL PILAR; GARCIA ARANDA MARIA ISABEL; GONZALEZ JOSÉ LORENZO; SANCHEZ FRÉDÉRIC
权利人:SERVIER LAB
摘要:Process for the synthesis of the compound of formula (I): n nApplication in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:US-7858828-B2
优先权日:2008-03-26
标 题 :Process for synthesis of (3R,3'R,6'R)-lutein and its stereoisomers
发明人：KHACHIK FREDERICK; CHANG AN-NI
权利人:UNIV MARYLAND
摘要:(3R,3′R,6′R)-Lutein and (3R,3′R)-zeaxanthin are two dietary carotenoids that are present in most fruits and vegetables commonly consumed in the US. These carotenoids accumulate in the human plasma, major organs, and ocular tissues. In the past decade, numerous epidemiological and experimental studies have shown that lutein and zeaxanthin play an important role in the prevention of age-related macular degeneration (AMD) that is the leading cause of blindness in the U.S. and Western World. The invention provides a process for the synthesis of (3R,3′R,6′R)-lutein and its stereoisomers from commercially available (rac)-α-ionone by a C 15 +C 10 +C 15 coupling strategy. In addition, the present invention also provides access to the precursors of optically active carotenoids with 3-hydroxy-ε-end group that are otherwise difficult to synthesize. The process developed for the synthesis of lutein and its stereoisomers is straightforward and has potential for commercialization.

专利号:US-7276637-B2
优先权日:2002-08-02
标题:Synthesis of cyclohexanone derivatives
发明人：BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD
权利人:MERCK & CO INC
摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.

专利号:US-4302612-A
优先权日:1976-07-15
标 题:Synthesis of perfluorodialdehydes
发明人：EVANS DAVID H; GREENWALD RICHARD B
权利人:POLAROID CORP
摘要:This invention is concerned with the synthesis of perfluorodialdehydes from the corresponding perfluorodiesters and with intermediates useful in the preparation of the perfluorodialdehydes.

专利号:US-8097720-B2
优先权日:2008-12-24
标题:Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：PEGLION JEAN-LOUIS; DESSINGES AIMEE; SERKIZ BERNARD; LERESTIF JEAN-MICHEL; LECOUVE JEAN-PIERRE
权利人:PEGLION JEAN-LOUIS; DESSINGES AIMEE; SERKIZ BERNARD; LERESTIF JEAN-MICHEL; LECOUVE JEAN-PIERRE; LAB SERVER
摘要:Process for the synthesis of ivabradine of formula (I): n nand addition salts thereof with a pharmaceutically acceptable acid.