CAS: 25569-53-3; Poly(Ethylene Glycol Succinate)

相似化合物

110-15-6 556-32-1 2226-88-2

丁二酸,乙二醇置于ti Isopropoxide 氮体系中,用 水 用作溶剂,化学反应生成聚丁二酸乙二醇酯(Degs)
参考文献:Poly(Meth)Acrylate Membranes For Separation Of Hydrocarbon Mixtures
标题:Poly(Meth)Acrylate Membranes For Separation Of Hydrocarbon Mixtures
摘要:本发明涉及一种聚合物化的含有公式i的聚酯的烃混合物分离方法:其中每个r和r2独立地是c6-C20芳香基残基或c1-C20脂肪基残基.每个r1独立地是氢或c1-C5烷基;"j"是1-1000范围内的整数.Z是一个杂原子或两个氢原子.本发明还涉及制备分离膜的方法.

专利信息

专利号:WO-2020012266-A1
优先权日:2018-07-12
标 题:Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase
发明人：GAO FENG; HARDEGGER LEO ALBERT; HUMAIR ROGER; KLEINBECK-RINIKER FLORIAN KARL; RAMPF FLORIAN ANDREAS; RUCH THOMAS; SCHLAMA THIERRY; WIETFELD BERNHARD
权利人:NOVARTIS AG
摘要:The present invention relates to a first biocatalytic process for preparing olodanrigan ((S)-5-(benzyloxy)-2-(2,2-diphenylacetyl)-6- methoxy-l,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; compound of formula (I); EMA401, PD 126055 ) by reacting 3-(2-(benzyloxy) -3-methoxyphenyl)propenoic acid (compound of formula (C3)) with an engineered phenylalanine ammonia lyase (PAL) and an amino donor to (S)-2-amino-3-(2-(benzyloxy)-3-methoxyphenyl)propanoic acid (compound of formula (C4)), and then reacting the compound of formula (C4) to olodanrigan, or a salt, or a solvate thereof. The present invention also relates to a second biocatalytic p rocess for preparing olodanrigan by reacting the compound of formula (C3) with an engineered phenylalanine ammonia lyase (PAL) and an amino donor, and then adding an aldehyde derivative to form (S)-5- (benzyloxy)-6-methoxy-l,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (compound of formula (C5)), and then reacting the compound of formula (C5) to olodanrigan, or a salt, or a solvate thereof. The present invention further relates to a process for preparing pharmaceuticals and pharmaceutical compositions from the compound of formula (I), or a salt, or a solvate thereof. Olodanrigan is used in the treatment of neuropathic and inflammatory pain.

专利号:US-2025144039-A1
优先权日:2022-07-13
标题:Compositions comprising surface modified globular nano-particles
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There are disclosed compositions comprising core-shell nano-elements composed in their core of a water-insoluble thermoplastic compound having a molecular weight of more than 0.6 kDa and in their shell of at least one fatty amine, or a part thereof, the core-shell nano-elements having a viscosity of 107 mPa·s or less and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less. The water-insoluble thermoplastic compound can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon application of the core-shell nano-elements to a surface to be treated therewith. Methods for preparing the composition and uses thereof are also provided.

专利号:CN-114057615-B
优先权日:2021-11-11
标题 :High-temperature-resistant polymerizable antibacterial agent, preparation thereof and application thereof in synthesis of antibacterial polyester

专利号:US-11220681-B2
优先权日:2017-01-19
标题 :Enzymatic reaction medium containing surfactant
发明人：GAI YU; GALLOU FABRICE; GAO FENG; GUO PENGFEI; KONG WEIYONG; PARMENTIER MICHAEL; ZHOU JIANGUANG
权利人:NOVARTIS AG
摘要:The present invention is directed to aqueous reaction mixtures for enzymatic synthesis reactions comprising a surfactant. The surfactant in the reaction mixture increases stability and yield of the enzymatic reaction. Furthermore, method for performing an enzymatic reaction using said aqueous reaction mixtures are provided.

专利号:CN-119060306-A
优先权日:2024-09-11
标 题 :Continuous synthesis method of poly (succinate)