CAS: 613-03-6; 1,2,4-Triacetoxybenzene

该化合物是一种苯衍生物,其中三个氢氧基组为乙基,形成含有分子分子式C12H12O6的化合物.该化学品主要用作有机合成的中间体,特别是用于生产药品,农用化学品和特殊化学品.其乙基结构增强了稳定性和反应性,使之适合在受控制条件下进行选择性转换.该化合物在普通有机溶剂中表现出良好的溶性,便于其在各种反应系统中使用.其明确界定的结构和一贯纯度使它成为研究人员和工业应用的可靠试剂,需要精确的芳香系统功能化.建议适当处理和储存以保持其完整性.

结构式图片

上下游产品

CAS号108-24-7 乙酸酐 | CAS号106-51-4 苯醌 | CAS号7298-33-1 1,2,4-tribenzyl... | CAS号78963-40-3 2L-(2,4/3,5)-2,... | CAS号64-19-7 冰醋酸 | CAS号533-73-3 1,2,4-苯三酚 | CAS号127-09-3 乙酸钠 | CAS号61885-19-6 methyl 2,3,6-tr... | CAS号488-76-6 环己五醇, L-栎醇 | CAS号529-84-0 4-甲基七叶亭 | CAS号533-73-3 1,2,4-苯三酚 | CAS号482-82-6 6,7-二羟基-4-苯基香豆素 | CAS号219305-27-8 9-(4-羧苯基)-3-氟 | CAS号2320-44-7 Spiro[isobenzof... | CAS号23368-41-4 3-Benzyl-6,7-di... | CAS号82747-36-2 6,7-二羟基-4-(三氟甲基)香豆素 | CAS号88404-14-2 6,7-二羟基香豆素-4-乙酸 | CAS号975-17-7 9-苯基-2,3,7-三羟基-6-荧光酮 | CAS号305-01-1 秦皮乙素

合成工艺路线路线简述

    (-)-Vibo-栎醇置于三氟甲磺酸三甲基硅酯体系中,化学反应 19.0H,反应生成 1,2,4-苯三酚醋酸酯
    参考文献:Transformation Of Quercitols Into 4-Methylenecyclohex-5-Ene-1,2,3-Triol Derivatives,Precursors For The Chemical Chaperones N-octyl-4-Epi-β-Valienamine (Noev) And N-octyl-β-Valienamine (Nov)
    标题:Transformation Of Quercitols Into 4-Methylenecyclohex-5-Ene-1,2,3-Triol Derivatives,Precursors For The Chemical Chaperones N-octyl-4-Epi-β-Valienamine (Noev) And N-octyl-β-Valienamine (Nov)
    摘要:(+)-原儿茶糖苷醇(1)和(-)-威博儿茶糖苷醇(2),这两种糖苷均可以通过肌醇的生物转化简便制备,成功转化为了相应的4-甲基环己-5-烯-1,2,3-三醇衍生物.研究证明,这些化合物在保留其构型的情况下,适合作为具有生物活性的氨基糖(如强效化学伴侣药物候选物n-辛基-4-表-β-戊吡胺醇(3)和n-辛基-β-戊吡胺醇(4))的前体. (以上译文仅供参考,英文原文版权为2011 Elsevier Ltd.所有,保留所有权利.)
    DOI:10.1016/j.Bmcl.2011.09.067

    海关参考信息

    专利信息


    专利号:US-12247239-B2
    优先权日:2019-06-21
    标题:Chemo-enzymatic process for the preparation of homopropargylic alcohol
    发明人:CHANDRASEKHAR SRIVARI; GHOSH SUBHASH; KRISHNA AVULA SHIVA; REDDY CHADA RAJI; SUDHAKAR GANGARAJULA; THENKRISHNAN KUMARAGURU; PABBARAJA SRIHARI; MAINKAR PRATHAMA SATYENDRA; NASAM RAJESH
    权利人:COUNCIL SCIENT IND RES; COUNCIL SCIENT IND RES
    摘要:The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12.

    专利号:WO-0056911-A1
    优先权日:1999-03-23
    标题 :Synthesis of 1,2,3,4-tetrahydroxybenzenes and 1,2,3-trihydroxybenzenes using myo-inositol-1-phosphate synthase and myo-inositol 2-dehydrogenase

    专利号:US-9963476-B2
    优先权日:2015-02-19
    标题 :Antioxidant compound having anti atherosclerotic effect and preparation thereof
    发明人:SRIGIRIDHAR KOTAMRAJU; SANTOSH KARNEWAR; BABU VASAMSETTI SATHISH; KUMAR TOGAPUR PAVAN; Reddy Basi Venkata Subba; Kumar Jerald Mahesh
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE −/− mice along with the endothelial cell age-delaying effects of Mito-Esc.

    专利号:CA-2640585-A1
    优先权日:2003-02-05
    标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one

    专利号:CA-2366222-A1
    优先权日:1999-03-23
    标 题:Synthesis of 1,2,3,4-tetrahydroxybenzenes and 1,2,3-trihydroxybenzenes using myo-inositol-1-phosphate synthase and myo-inositol 2-dehydrogenase

    专利号:US-6287798-B1
    优先权日:1996-05-01
    标题 :Esculetin derivatives
    发明人:JAMES ARTHUR; ARMSTRONG LYLE
    权利人:IDG UK LTD
    摘要:The invention concerns novel 6- or 7-substituted derivatives of esculetin (6,7-dihydroxy-2H-1-benzopyran-2-one), their synthesis, and their application as substrates for the detection of micro-organisms in samples where a derivative is enzymatically cleaved to release a colored or fluorogenic marker which has a low tendency to diffuse through agar or other aqueous environments.
    湖北巨龙堂医药化工有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.jltpharm.com
    企业联系电话:027-82609301👤
    📞湖北巨龙堂医药化工有限公司 ⚠️参考联系方式
    联系人:张经理
    电话:027-82609301
    手机:13971342059

    邮箱:798308538@qq.com
    通信地址: 武汉市江汉区常青路106号
    邮编: 430000
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:武汉市江汉区常青路106号
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    第 1 / 1 页
    现货

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Nataly D Pokhilo, Et Al. Synthesis Of Echinamines A And B, The First Aminated Hydroxynaphthazarins Produced By The Sea Urchin Scaphechinus Mirabilis And Its Analogues. J Nat Prod. 2006 Aug;69(8):1125-9.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    参考文献:10.1038/nchem.1506
    摘要:Over B, Wetzel S, Grütter C, Nakai Y, Renner S, Rauh D, Waldmann H. Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem. 2013 Jan;5(1):21–8. doi: 10.1038/nchem.1506.
    参考文献:10.1021/np0502185
    摘要:Pokhilo ND, Shuvalova MI, Lebedko MV, Sopelnyak GI, Yakubovskaya AY, Mischenko NP, Fedoreyev SA, Anufriev VP. Synthesis of Echinamines A and B, the First Aminated Hydroxynaphthazarins Produced by the Sea Urchin Scaphechinus mirabilis and Its Analogues. J. Nat. Prod. 2006 Jul 19;69(8):1125–9. doi: 10.1021/np0502185.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知