CAS: 125-10-0; 2-((8S,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-Dimethyl-3,11-Dioxo-6,7,8,9,10,11,12,13,14,15,16,17-Dodecahydro-3H-Cyclopenta[a]Phenanthren-17-yl)-2-Oxoethyl Acetate

上下游产品

CAS号52-21-1 醋酸泼尼松龙 | CAS号50-24-8 泼尼松龙 | CAS号28449-43-6 (17Z)-11beta,21... | CAS号50-04-4 醋酸可的松 | CAS号53-03-2 泼尼松 | CAS号108-24-7 乙酸酐 | CAS号3044-42-6 2-((8S,9S,10R,1... | CAS号17652-24-3 [2-[(8S,9S,10R,... | CAS号53-03-2 泼尼松

醋酸泼尼松龙置于2-碘酰基苯甲酸体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 5.0H,以99%的收率获得醋酸泼尼松
参考文献:O-Iodoxybenzoic Acid In Dimethylformamide As A Convenient Reagent For The Oxidation Of Alcohols To Aldehydes And Ketones
标题:O-Iodoxybenzoic Acid In Dimethylformamide As A Convenient Reagent For The Oxidation Of Alcohols To Aldehydes And Ketones
摘要:Dmf Dissolves O-Iodoxybenzoic Acid (Up To 0.1 Mol Dm(-3)) And,Therefore,Is A Solvent Of Choice For The Reactions With O-Iodoxybenzoic Acid Simplifying Significantly A Product Isolation Procedure Due To A Higher Volatility. The Reaction Rate And Selectivity Of The Oxidation Of Alcohols To Corresponding Carbonyl Compounds With O-Iodoxybenzoic Acid In Dmf Are Close To Those In Dmso.
Doi:10.1016/j.Mencom.2008.11.007

专利信息

专利号:US-9051302-B2
优先权日:2008-01-15
标 题 :Synthesis of resorcylic acid lactones useful as therapeutic agents
发明人：WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN
权利人:WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN; UNIV STRASBOURG
摘要:Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.

专利号:US-10239856-B2
优先权日:2008-01-15
标题:Synthesis of resorcylic acid lactones useful as therapeutic agents

专利号:CN-101990399-B
优先权日:2008-01-15
标 题:Synthesis of dihydroxybenzoic acid lactones as therapeutic agents

专利号:US-2011217335-A1
优先权日:2008-01-15
标 题 :Synthesis of resorcylic acid lactones useful as therapeutic agents

专利号:US-2016075677-A1
优先权日:2008-01-15
标 题:Synthesis of resorcylic acid lactones useful as therapeutic agents

专利号:CN-120366248-A
优先权日:2025-04-23
标 题:A 3-sterol-Δ1-dehydrogenase mutant and its application in the synthesis of prednisone acetate