CAS: 464-92-6; (1S,2R,4As,6As,6Br,8Ar,9R,10R,11R,12Ar,12Br,14Bs)-10,11-Dihydroxy-9-(Hydroxymethyl)-1,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2H)-Carboxylic Acid

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CAS号16830-15-2 积雪草苷

积雪草苷置于甲醇,Sodium Hydroxide体系中,化学反应生成 积雪草酸
参考文献:含有[小α]-氨基膦酸酯的新型积雪草酸衍生物的合成,抗增殖和诱导细胞凋亡的作用
标题:含有[小α]-氨基膦酸酯的新型积雪草酸衍生物的合成,抗增殖和诱导细胞凋亡的作用
摘要:这是已接受的手稿,已通过rsc出版同行评审过程,并已被接受出版.接受的手稿在接受后不久就会在线发布.一旦可用,此版本的文章将被完全编辑,格式化并提供高级阅读的高级文章代替.
DOI:10.1039/c6Ra11397D

专利信息

专利号:US-5955083-A
优先权日:1996-01-03
标 题 :Use of eriobotrya japonica extract, in particular in cosmetics for stimulating glycosaminoglycan synthesis
发明人：BONTE FREDERIC; DUMAS MARC
权利人:LVMH RECH
摘要:PCT No. PCT/FR97/00009 Sec. 371 Date Aug. 28, 1997 Sec. 102(e) Date Aug. 28, 1997 PCT Filed Jan. 3, 1997 PCT Pub. No. WO97/06659 PCT Pub. Date Feb. 27, 1997The invention concerns novel uses of an Eriobotrya japonica extract, in particular in cosmetics or pharmaceutics. This extract permits stimulation of glycosaminoglycan synthesis, in particular of hyaluronic acid, thus imparting to the cosmetic compositions containing this extract the properties of improving the firmness and suppleness of the skin, combating the formation of wrinkles or lessening the depth thereof, smoothing the surface of the skin by means of a tightening effect, or moisturizing the skin. The invention further concerns the use of these extracts for stimulating the synthesis of glycosaminoglycans from a cell culture medium, in particular fibroblasts or keratinocytes.

专利号:US-2023157936-A1
优先权日:2021-11-24
标 题 :Anti-aging skin peel composition and method of application
发明人：ZAHR ALISAR; NGUYEN THU Q; KOCH JOHN; KELLY TATIANA
权利人:JAMRM LLC
摘要:A skincare composition and a method for removing layers of skin in a cosmetic procedure. The skincare composition comprises active ingredients mixed into a cosmetically acceptable carrier. The active ingredients include an effective amount of one or more keratolytic agents for inducing a desired degree of keratolysis in the skin, an effective amount of one or more free radical neutralizing agents for negating cellular damage from reactive chemical species, and an effective amount of one or more agents increasing synthesis of dermal components. The one or more free radical neutralizing agents and the one or more agents increasing synthesis of dermal components are acids in their un-neutralized, natural acid form, and a total amount of the active ingredients is less than 50 w/w% of the skincare composition, and a pH of the skincare composition is between 1.5-3.5.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2022162188-A1
优先权日:2019-01-15
标 题:Isoprenoids and methods of making thereof
发明人：WILLIAMS GAVIN; LUND SEAN; HALL RACHAEL
权利人:UNIV NORTH CAROLINA STATE
摘要:Disclosed are methods for preparing isoprenoid subunits, as well as methods of employing these isoprenoid subunits for the synthesis of isoprenoids. Also provided are isoprenoids prepared using the methods described herein.

专利号:US-5747538-A
优先权日:1994-03-18
标 题 :Use of ginsenoside R0 or a plant extract containing same to promote collagen synthesis
发明人：MEYBECK ALAIN; BONTE FREDERIC; DUMAS MARC; CHAUDAGNE CATHERINE
权利人:LVMH RECH
摘要:PCT No. PCT/FR95/00326 Sec. 371 Date Sep. 18, 1996 Sec. 102(e) Date Sep. 18, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25524 PCT Pub. Date Sep. 28, 1995The use of ginsenoside R0 or a plant extract containing same to prepare a cosmetic or pharmaceutical composition, particularly a skin care composition, for promoting collagen synthesis, particularly collagen I and/or collagen III synthesis. Said cosmetic or pharmaceutical composition is administered to a mammal, particularly a human being, in order to promote collagen synthesis. A method for promoting collagen synthesis in fibroblast growth media is also disclosed.

专利号:US-2024301461-A1
优先权日:2023-01-17
标题:Recombinant Escherichia Coli for Expressing Synthesis Pathway of Asiaticoside and Application Thereof
发明人：ZHOU JINGWEN; ZENG WEIZHU; ZHAO XINGYING; XU SHA; CHEN JIAN
权利人:UNIV JIANGNAN
摘要:The present disclosure discloses recombinant Escherichia coli for expressing a synthesis pathway of asiaticoside and application thereof, and belongs to the field of bioengineering. Rhamnosyltransferase with an amino acid sequence shown in any one of SEQ ID NO: 25 to SEQ ID NO: 29, glucosyltransferase with an amino acid sequence shown in any one of SEQ ID NO: 10 to SEQ ID NO: 17 and UGT73AH1 reported in a document are transferred into E. coli BL21 (DE3)Δpgi to realize co-expression. Fermentation results show that all 5 rhamnosyltransferases screened in the present disclosure can achieve effects, and a unique new peak appears at 0.596 min, which is consistent with a characteristic ion flow of an asiaticoside standard product. According to the present disclosure, barriers of the prior art are broken through, a new biosynthesis method for asiaticoside is provided, and industrialization of biosynthesis of asiaticoside becomes possible.