CAS: 71830-08-5; (1R,3S)-3-Aminocyclopentanecarboxylic Acid

该化合物是白色至非白色的固体,由于极地碳oxylic酸和氨基酸组的存在而溶于水中;该化合物对药用化学和生物化学具有兴趣,因为它可以作为石化合成的建筑块或潜在的治疗剂;其特性,如熔点,沸点和再活性,可以因环境条件和其他功能组的存在而有所变化;此外,其立体化学特性可能会影响其与生物目标的结合性,从而成为药物设计和开发的研究对象.

英文名称(1R,3S)-3-Aminocyclopentanecarboxylic Acid
中文名称(1R,3S)-(-)-3-氨基环戊烷羧酸
IUPAC名称(1R,3S)-3-aminocyclopentane-1-carboxylic acid
其它别名(1R,3S)-3-Aminocyclopentanecarboxylic Acid; (1R,3S)-3-Aminocyclopentane-1-Carboxylic Acid; (-)-(1R,3S)-3-Aminocyclopentanecarboxylic Acid; Cis-3-Aminocyclopentanecarboxylic Acid; (1R,3S)-3-Amino-Cyclopentanecarboxylic Acid; (1R
CAS编号71830-08-5
MFCD编号:MFCD00211289
EINECS号:676-949-5
分子式:C6H11NO2
分子量:129.16
产品CID: 2509568
产品分类生物化工 → 氨基酸及其衍生物 → 其他氨基酸衍生物

相似结构搜索
产品信息参考;;;;
InChIKey: MLLSSTJTARJLHK-UHNVWZDZSA-N
InChI=1S/C6H11NO2/c7-5-2-1-4(3-5)6(8)9/h4-5H,1-3,7H2,(H,8,9)/t4-,5+/m1/s1…
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数1.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P261-P280a-P304+P340-P305+P351+P338-P405-P501a
危险品标志Xn
安全声明22-26-36/37/39
危险类别码20/21/22-36/37/38-22

上下游产品

(1R,3S)-3-Is°Cyanato-cyclopentanecarboxylic acid cis-1,3-cyclopentanedicarboxylic acid (1R,3S)-dimethyl cyclopentane-1,3-dicarboxylate (+)-cis-(1S,3R)-3-carbomethoxycyclopentane carboxylic acid (1R,3S)-3-(9-fluorenylmethoxycarbonylamino)cyclopentanecarboxylic acid (1R,3S)-methyl 3-amin°Cyclopentanecarboxylate hydr°Chloride (1R,3S)-3-(4-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)phenylamino)cyclopentanecarboxylic acid (1S,3R)-3-amino-cyclopentanecarboxylic acid methyl ester hydr°Chloride

合成工艺路线路线简述

合成目标产物 (1R,3S)-3-Aminocyclopentanecarboxylic Acid 主要起始原料 2-Azabicyclo[2.2.1]Heptan-3-One
(文献来源)合成步骤主要原料 2-Azabicyclo[2.2.1]Heptan-3-One

(1R,3S)-Dimethyl Cyclopentane-1,3-Dicarboxylate置于盐酸,Sodium Azide,Phosphate Buffer,三乙胺体系中,用甲醇,水,丙酮,甲苯,乙腈作为反应溶剂,化学反应生成 (1R,3S)-3-氨基环戊羧酸
参考文献:Enantioselective Synthesis Of (+) And (-)-Cis-3-Aminocyclo-Pentanecarboxylic Acids By Enzymatic Asymmetrization
标题:Enantioselective Synthesis Of (+) And (-)-Cis-3-Aminocyclo-Pentanecarboxylic Acids By Enzymatic Asymmetrization
摘要:Both Enantiomers Of Cis-3-Aminocyclopentanecarboxylic Acid (Gaba Analogs,Inhibitory Neurotransmitter) Have Been Prepared Via Enzymatic Asymmetrization Of Cis-1,3-Cyclopentanedicarboxylic Acid.
DOI:10.1016/s0957-4166(00)80189-5