CAS: 35166-33-7; 3-Hydroxymethyl-5-Methylisoxazole

相似化合物

19788-35-3 3209-72-1 3405-77-4

上下游产品

5-甲基异恶唑-3-甲酸 5-Methylisoxazole 3-Carboxylic Acid 3405-77-4
5-甲基异恶唑-3-羧酸甲酯 Methyl 5-Methylisoxazole-3-Carboxylate 19788-35-3

乙酰丙酮酸乙酯置于lithium Aluminium Tetrahydride,盐酸羟胺体系中,用 四氢呋喃,乙醇 作为反应溶剂,化学反应 2.5H,反应生成 3-羟甲基-5-甲基异恶唑
参考文献:3-氨基甲基-5-取代的异恶唑的区域选择性合成:使用1,3-丙二酚作为催化剂,通过硼氢化钠将叠氮化物快速简便地化学选择性还原为胺.
标题:3-氨基甲基-5-取代的异恶唑的区域选择性合成:使用1,3-丙二酚作为催化剂,通过硼氢化钠将叠氮化物快速简便地化学选择性还原为胺.
摘要:使用1,3-丙二硫醇作为催化剂,通过硼氢化钠将一系列异恶唑叠氮化物选择性地还原为异恶唑胺,并获得定量收率.
DOI:10.1016/s0040-4039(00)60386-6

专利信息

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-2003069305-A1
优先权日:2000-12-22
标题:Pharmaceutical uses and synthesis of benzobicyclooctanes

专利号:WO-02051851-A2
优先权日:2000-12-22
标题:Pharmaceutical uses and synthesis of benzobicyclooctanes