CAS: 434-22-0; Nandrolone

上下游产品

(10)-diene3-methoxy-17-hydroxyestra-2,5(10)-diene 17β-hydroxy-estr-5(10)-en-3-one 3-methoxyestra-1,3,5(10),8(9)-tetraen-17β-ol estra-4-ene-3,17-dioneestradiol estra-4-ene-3,17-dione 17β-acetoxy-5α-estran-3-one 17β-acetoxy-5β-estran-3-one

(1S,7As)-1-Hydroxy-7A-Methyl-2,3,7,7A-Tetrahydro-1H-Inden-5(6H)-One置于磷酸,Palladium 10% On Activated Carbon,三氟化硼乙醚,氢气,Sodium Methylate,三乙胺,Sodium Hydroxide体系中,用 甲醇,乙醇,二氯甲烷,水 作为反应溶剂,化学反应 11.0H,反应生成 诺龙
参考文献: C-20 Steroid Compounds,Compositions And Uses Thereof To Treat Traumatic Brain Injury (Tbi),Including Concussions[fr] Composés Stéroïdes En C-20,Compositions Et Utilisations Associées Pour Traiter Une Lésion Cérébrale Traumatique (Tbi),Notamment Des Commotions
标题: C-20 Steroid Compounds,Compositions And Uses Thereof To Treat Traumatic Brain Injury (Tbi),Including Concussions[fr] Composés Stéroïdes En C-20,Compositions Et Utilisations Associées Pour Traiter Une Lésion Cérébrale Traumatique (Tbi),Notamment Des Commotions
摘要:本发明涉及c-20类固醇化合物,其组合物和使用方法,用于治疗,减轻和/或预防创伤性脑损伤(tbi),包括严重tbi,中度tbi和轻度tbi,包括脑震荡.

专利信息

专利号:US-6350739-B1
优先权日:1999-08-11
标 题:Methods of prevention and treatment of ischemic damage
发明人：SIMPKINS JAMES W; COVEY DOUGLAS F
权利人:UNIV FLORIDA RESARCH FOUNDATIO; UNIV WASHINGTON
摘要:The present invention in various embodiments provides methods of treating stroke and conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) administering the effective amount of the compound over a course that includes at least one dose within a time that is effectively proximate to the ischemic event, so as to confer protection on the population of cells. Novel methods are provided for the delivery of an estrogen compound. Examples of ischemic events treatable according to the invention are cerebrovascular disease or stroke, subarachnoid subhemorrhage, myocardial infarct, surgery and trauma. A method of treating ischemic damage utilizing hormones that are non-sex hormones is also provided. A method of treating stroke with ent-17β-estradiol, and a method of synthesis, and compounds produced from the synthesis are provided.