CAS: 5177-27-5; 5-Amino-2,4-Dichloropyrimidine

相似化合物

49845-33-2 91322-00-8 54660-78-5

上下游产品

2,4-Dichloro-5-nitropyrimidine 5-Aminouracil 2,4-dichloro-5-nitropyridine 2,4-dimethoxypyrimidin-5-ylamine 4-ethylmercapto-2-chloro-pyrimidin-5-ylamine pyrimidin-5-amine 2-chloro-4-methoxypyrimidine-5-ylamine

2,4-二氯-5-硝基吡啶置于铁粉体系中,用 溶剂黄146 作为反应溶剂,化学反应 1.0H,反应生成 5-氨基-2,4-二氯嘧啶
参考文献: Trka Kinase Inhibitors,Compositions And Methods Thereof[fr] Inhibiteurs De La Kinase Trka,Compositions En Contenant Et Méthodes Associées
标题: Trka Kinase Inhibitors,Compositions And Methods Thereof[fr] Inhibiteurs De La Kinase Trka,Compositions En Contenant Et Méthodes Associées

专利信息

专利号:WO-2022090101-A1
优先权日:2020-10-26
标题 :Process for synthesis of 2,4-dichloro-5-aminopyrimidine
发明人：GROLL KLAUS; PANGERL MICHAEL; WANG YANLING; XING LIDONG; XU JIANPING; ZHANG PINJIE; ZHANG YONGSHENG; ZHU ZHIBIN
权利人:BOEHRINGER INGELHEIM INT
摘要:The invention is directed to the commercially synthetic process of 2,4-Dichloro-5-amino- pyrimidine, starting from 5-nitrouracil.

专利号:US-2011166152-A1
优先权日:2008-10-02
标题 :Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
权利人:LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
摘要:Heteroaromatic compounds of structural formula (I) are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis.

专利号:US-9351974-B2
优先权日:2011-11-10
标题 :Substituted pteridinones for the treatment of cancer
发明人：JIN MEIZHONG; KADALBAJOO MRIDULA; LI AN-HU; MULVIHILL MARK J; SIU KAM W; STEINIG ARNO G; WANG JING
权利人:OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula I, as shown below and defined herein: n npharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven or mediated at least in part by RSK. This Abstract is not limiting of the invention.

专利号:CN-119569659-A
优先权日:2024-12-13
标 题 :Synthesis of 5-Chloro-2,4-diphenylpyrimidine