CAS: 56038-13-2; (2R,3R,4R,5R,6R)-2-(((2R,3S,4S,5S)-2,5-Bis(Chloromethyl)-3,4-Dihydroxytetrahydrofuran-2-yl)Oxy)-5-Chloro-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4-Diol

上下游产品

sucralose-6-acetate N-benzyl-N,N,N-triethylammonium chloride sucrose-6-acetate Trimethyl orthoacetate3,6-anhydro-4-chloro-4-deoxy-α-D-galactopyranosyl 3,4-anhydro-1,6-dichloro-1,6-dideoxy-β-D-lyxo-hexulofuranoside 4-chloro-4-deoxy-α-D-galactopyranosyl 3,4-anhydro-1,6-dichloro-1,6-dideoxy-β-D-lyxo-hexulofuranoside 6-O-tert-butyldiphenylsilyl-4-chloro-4-deoxy-α-D-galactopyranosyl 1,6-dichloro-1,6-dideoxy-β-D-fructofuranoside 6-O-tert-butyldiphenylsilyl-4-chloro-4-deoxy-α-D-galactopyranosyl 3,4-anhydro-1,6-dichloro-1,6-dideoxy-β-D-lyxo-hexulofuranoside

3,4-Di-O-Acetyl-1,6-Dichloro-1,6-Dideoxy-β-D-Fructofuranosyl 2,3,6-Tri-O-Acetyl-4-Chloro-4-Deoxy-α-D-Glucopyranoside置于甲醇,Sodium Methylate体系中,化学反应 2.0H,以93%的收率获得产物三氯蔗糖
参考文献:Wo2008/96928
标题:Wo2008/96928

专利信息

专利号:WO-2007096726-A3
优先权日:2006-02-20
标 题 :Process for the preparation of a glucose derivative
发明人：GHARPURE MILIND MORESHWAR; BHAWAL BABURAO MANIKRAO; ZOPE UMESH REWAJI; DESHMUKH SANJAY SHANKAR; SONAWANE SWAPNIL PANDITRAO; MEHTA SATISH RAMNALAL
权利人:EMCURE PHARMACEUTICALS LTD; GHARPURE MILIND MORESHWAR; BHAWAL BABURAO MANIKRAO; ZOPE UMESH REWAJI; DESHMUKH SANJAY SHANKAR; SONAWANE SWAPNIL PANDITRAO; MEHTA SATISH RAMNALAL
摘要:The present invention relates to an improved, safe, commercially viable, cost effective and eco friendly process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose (Sucralose). The invention is directed towards the convenient synthesis of 2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS) from 6,1',6'-tri-O-trityl-penta-O-acetyl sucrose ('TRISPA').

专利号:US-2003158404-A1
优先权日:2000-07-31
标题:Method for the synthesis of sucrose-6-esters

专利号:AU-2008204386-A1
优先权日:2007-01-09
标 题 :Method for the synthesis of sucrose-6-esters

专利号:US-5126438-A
优先权日:1990-12-07
标题 :6,6'-dihalo-6,6'-dideoxy-1',2,3,3',4,4'-hexa-o-methylsucrose compounds
发明人：SACHINVALA NAVZER D
权利人:HAWAIIAN SUGAR PLANTERS ASSOC
摘要:6,6'-dihalo-6,6'-dideoxy-1',2,3,3',4,4'-hexa-O-methylsucrose compounds are disclosed as useful intermediates for the synthesis of water-absorbent polyethers. These compounds may also be used as intermediates in the preparation of other difunctional monomers and metal complexing agents from sucrose.

专利号:US-2015329593-A1
优先权日:2014-05-19
标题:Synthesis of Beta-Arrestin Effectors

专利号:EP-1305326-B1
优先权日:2000-07-31
标 题 :An improved method for the synthesis of sucrose-6-esters