CAS: 6640-25-1; (4-Chlorophenyl)(Cyclopropyl)Methanone

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CAS号637-87-6 对氯碘苯 | CAS号4023-34-1 环丙甲酰氯 | CAS号40877-09-6 4,4'-二氯苯丁酮 | CAS号108-90-7 氯苯 | CAS号4635-59-0 4-氯丁酰氯 | CAS号106-39-8 对氯溴苯 | CAS号5500-21-0 环丙基腈 | CAS号18228-43-8 4-氯-alpha-氯丙基苄醇 | CAS号18228-43-8 4-氯-alpha-氯丙基苄醇 | CAS号104271-30-9 8-(4-chlorophen... | CAS号31545-26-3 4-氯-3-硝基苯环丙烷甲酮 | CAS号123312-22-1 1-(4-氯苯基)-1-环丙基甲胺 | CAS号65362-97-2 ethyl 3-(4-chlo... | CAS号83929-31-1 1-chloro-4-[4-c... | CAS号92854-06-3 1,1-双-(4-氯苯基)-1... | CAS号62586-85-0 4-氯-alpha-环丙基-a...

4,4'-二氯苯丁酮置于sodium Hydroxide体系中,用 乙醇 作为反应溶剂,以83.7%的收率获得产物4-氯苯基环丙基甲酮
参考文献:一种制备4-环丙亚甲基苯硼酸的方法
标题:一种制备4-环丙亚甲基苯硼酸的方法
摘要:本发明公开了一种制备4‑环丙亚甲基苯硼酸的方法,涉及有机合成技术领域,以氯苯作为初始原料,先经傅克酰基化反应反应生成4‑氯丁酰基氯苯,再经环合反应反应生成4‑环丙甲酰基氯苯,然后经还原反应反应生成4‑环丙亚甲基氯苯,最后经格氏硼酸化反应制得4‑环丙亚甲基苯硼酸.本发明以价廉易得的氯苯作为起始原料,显著降低制备成本,经傅克酰基化反应,环合反应,还原反应,格氏硼酸化反应制得产物4‑环丙亚甲基苯硼酸,总摩尔收率最高能达到35%以上,在低成本的基础上保证了产物的反应生成量,从而适用于工业化生产.

专利信息

专利号:US-4158015-A
优先权日:1978-08-16
标 题:Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes
发明人：PAUL JILL H
权利人:MOBIL CORP
摘要:Mixtures of the E and Z isomers of aryl alkyl oximes are converted to 98% or greater E isomer by a process comprising treating a solution of a mixture of E and Z isomers in an organic solvent with a protic or Lewis acid, under anhydrous conditions, to precipitate >98% pure E isomer of an immonium complex and treating (neutralizing) the precipitate with an excess of dilute organic/inorganic base, such as Na 2 CO 3 or NaHCO 3 . The E isomer of the ketoxime is a precursor for highly insecticidal ketoximinoethers.

专利号:EP-0009865-A1
优先权日:1978-08-16
标题:Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes