CAS: 16042-25-4; 2-Imidazolecarboxylic Acid

相似化合物

10111-08-7 33543-78-1 17334-09-7

上下游产品

CAS号33543-78-1 咪唑-2-甲酸乙酯 | CAS号19213-72-0 1-乙氧甲酰咪唑 | CAS号163769-73-1 2-(trichloromet... | CAS号124-38-9 二氧化碳 | CAS号61278-81-7 1-(二乙氧基甲基)咪唑 | CAS号288-32-4 咪唑 | CAS号124-38-9 二氧化碳 | CAS号17334-09-7 1H-咪唑-2-羧酸甲酯 | CAS号64736-53-4 4,5-二氯-1H-咪唑-2-羧酸 | CAS号66675-22-7 2-(三氟甲基)-1H-咪唑 | CAS号79711-73-2 5H,10H-Diimidaz... | CAS号920511-25-7 [4-(3-fluoroani... | CAS号63678-16-0 2-Imidazolecarb...

2,2,2-Trifluoro-1-(1H-Imidazol-2-yl)-Ethane-1,1-Diol置于sodium Hydroxide体系中,化学反应生成咪唑-2-甲酸
参考文献:五氟乙基咪唑的合成及碱解
标题:五氟乙基咪唑的合成及碱解
摘要:组胺和l-组氨酸甲酯的n-三氟乙酰基衍生物被五氟乙基自由基的光化学环取代提供相应的2-和4-五氟乙基化产物,产率分别为19%和27%.碱水解将2-五氟乙基转化为三氟乙酰基.涉及二氮杂富烯中间体的反应机理类似于对(三氟甲基)咪唑的阐明.但是,五氟乙基比三氟甲基对水解的反应性强.对于咪唑衍生物,反应性比率在c-2处为75,在c-4处为40.4-(五氟乙基)组胺的水解得到双环产物4-(三氟甲基)-6,7-二氢-1H-咪唑并[4,5-C]-吡啶,产率为65.4%.
Doi:10.1016/s0022-1139(00)81992-2

专利信息

专利号:US-6683189-B1
优先权日:1996-02-26
标 题 :Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
发明人：DERVAN PETER B; BAIRD ELDON
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.

专利号:US-2022297083-A1
优先权日:2019-08-27
标 题 :Continuous Synthesis Of Porous Coordination Polymers In Supercritical Carbon Dioxide
发明人：RASMUSSEN ELIZABETH G; KRAMLICH JOHN C; NOVOSSELOV IGOR V
权利人:UNIV WASHINGTON
摘要:This disclosure relates generally relates to methods and systems useful for continuous synthesis of materials in super-critical carbon dioxide (sCO 2 ). More particularly, this disclosure relates to methods and systems useful for continuous synthesis of coordination polymers, such as metal-organic frameworks (MOFs) and/or covalent organic frameworks (COFs), in sCO 2 .

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-10919904-B2
优先权日:2016-08-17
标 题 :Northern-southern route to synthesis of bacteriochlorins
发明人：LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU
权利人:UNIV NORTH CAROLINA STATE
摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).

专利号:WO-2017089470-A1
优先权日:2015-11-27
标 题:Process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases
发明人：HOFMANN DAGMAR; HOFMANN JOSEFA; HEINRICH MARKUS
权利人:Friedrich-Alexander-Universität Erlangen-Nürnberg
摘要:The present invention relates to a process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases.

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.