CAS: 16874-33-2; Tetrahydrofuran-2-Carboxylic Acid

相似化合物

87392-07-2 87392-05-0 22415-59-4

上下游产品

CAS号97-99-4 四氢糠醇 | CAS号88-14-2 糠酸; 2-糠酸; 2-呋喃甲酸 | CAS号542-28-9 δ-戊内酯 | CAS号109-52-4 正戊酸 | CAS号98-01-1 糠醛 | CAS号7326-46-7 2-FURANOL,TETRA... | CAS号83867-84-9 allyl ester of ... | CAS号70-26-8 鸟氨酸 | CAS号64-19-7 冰醋酸 | CAS号37443-42-8 2-四氢糠酸甲酯 | CAS号141060-98-2 Ethanone, 2-chl... | CAS号91470-28-9 四氢呋喃-2-甲酰胺 | CAS号109-99-9 四氢呋喃 | CAS号81403-68-1 盐酸阿夫唑嗪 | CAS号81403-80-7 阿夫唑嗪 | CAS号87392-07-2 (S)-(-)-四氢呋喃-2-羧酸 | CAS号81403-67-0 N-(3-甲胺基丙基)四氢呋喃... | CAS号97-99-4 四氢糠醇 | CAS号87392-05-0 (R)-(+)-四氢呋喃-2-甲酸

糠醛置于poly[4-(Diacetoxyiodo)Styrene],2,2,6,6-Tetramethyl-Piperidine-N-Oxyl体系中,用 丙酮 用作溶剂,化学反应 24.0H,反应生成2-四氢呋喃甲酸
参考文献:Tempo 介导的伯醇与聚 [4-(二乙酰氧基碘) 苯乙烯] 环境无害氧化成羧酸
标题:Tempo 介导的伯醇与聚 [4-(二乙酰氧基碘) 苯乙烯] 环境无害氧化成羧酸
摘要:使用 Tempo 介导的聚 [4-(二乙酰氧基碘)苯乙烯] 系统在丙酮和水中进行了操作简单且环境友好的伯醇氧化为相应的羧酸.
Doi:10.1055/s-2004-830881

专利信息

专利号:US-12391691-B2
优先权日:2018-11-16
标题:Synthesis of key intermediate of KRAS G12C inhibitor compound
发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-2024199566-A1
优先权日:2022-11-16
标题:Catalytic synthesis of delta-valerolactone (dvl) from furfural-derived 2-hydroxytetrahydropyran (hthp)
发明人：HUBER GEORGE; DASTIDAR RAKA; JOHNSTONE SAM; MCCLELLAND DANIEL
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method to make delta-valerolactone (“DVLâ€?) by dehydrogenating 2-hydroxytetrahydropyran (“HTHPâ€?). The HTHP is contacted with a supported-metal catalyst for a time, at a temperature, and at a pressure wherein at least a portion of the HTHP is converted to DVL via dehydrogenation of the HTHP. The HTHP may be derived from biomass. Thus, the method yields DVL without requiring a petroleum-based feedstock.

专利号:WO-2009001369-A1
优先权日:2007-06-22
标 题 :An improved process for the preparation of alfuzosin hydrochloride
发明人：DEO KESHAV; DESAI SANJAY; RATHOD DHIRAJ MOHANSINH; PARIKH CHIRAG CHANDRAKANT; PATEL RIPALKUMAR KANTIBHAI
权利人:ALEMBIC LTD; DEO KESHAV; DESAI SANJAY; RATHOD DHIRAJ MOHANSINH; PARIKH CHIRAG CHANDRAKANT; PATEL RIPALKUMAR KANTIBHAI
摘要:The present invention relates to an improved process for the preparation of Alfuzosin hydrochloride of formula (I) comprising a step of reacting compound of formula (IV) with compound of formula (V) in presence of aprotic solvent to obtain compound of formula (III) which is a useful intermediate for synthesis of Alfuzosin hydrochloride of formula (I).

专利号:US-9944869-B2
优先权日:2007-03-08
标 题 :Synthesis of liquid fuels and chemicals from oxygenated hydrocarbons
发明人：CORTRIGHT RANDY D; BLOMMEL PAUL G
权利人:VIRENT INC
摘要:Processes and reactor systems are provided for the conversion of oxygenated hydrocarbons to hydrocarbons, ketones and alcohols useful as liquid fuels, such as gasoline, jet fuel or diesel fuel, and industrial chemicals. The process involves the conversion of mono-oxygenated hydrocarbons to aromatics and gasoline range hydrocarbons where the oxygenated hydrocarbons are derived from biomass.