CAS: 459-04-1; 4-Fluorophenylacetyl Chloride

上下游产品

p-Fluorophenylacetic acid p-fluorotoluene 4-fluorophenylacetonitrile 4-Fluorobenzyl bromide (4-fluoro-phenyl)-acetic acid-(2-piperidino-ethyl ester) 2-(4-Fluorophenyl)-1-(4-methoxyphenyl)ethan-1-one 4,4'-difluorodeoxybenzoin 2-(4-fluorobenzyl)benzo[d]thiazole

对氟甲苯置于n-溴代丁二酰亚胺(Nbs),氯化亚砜体系中,化学反应生成 对氟苯乙酰氯
参考文献:Adcock,W. Et Al.,Australian Journal Of Chemistry,1970,Vol. 23,P. 1921-1937
标题:Adcock,W. Et Al.,Australian Journal Of Chemistry,1970,Vol. 23,P. 1921-1937

专利信息

专利号:US-5623068-A
优先权日:1994-03-07
标 题:Synthesis of DNA using substituted phenylacetyl-protected nucleotides
发明人：REDDY M PARAMESWARA; FAROOQUI FIRDOUS; HANNA NAEEM B
权利人:BECKMAN INSTRUMENTS INC
摘要:Deoxyribonucleotide and ribonucleotide derivatives of the general formula I I wherein R1 represents -CR'R''-Ar, in which Ar is substituted aryl (as hereinafter defined) and R' and R'' are independently selected from the group consisting of hydrogen and lower alkyl; one of -R2 and R3 is a hydroxyl-protecting group and the other is a group suitable for synthesis of polynucleotides or for attachment of the nucleotide to a solid support; R4 is selected from the group consisting of hydrogen, -OH and protected hydroxyl; and B represents a divalent radical corresponding to a purine or pyrimidine base. When synthesis is carried out using these derivatives, the deprotection procedure is reduced to an essentially instantaneous process. The derivatives have acceptable shelf life and are very stable to conventional DNA synthesis conditions. Particularly preferred are those compounds wherein Ar is mono- and dihalo-substituted phenyl.

专利号:US-4803280-A
优先权日:1986-07-08
标题:Substituted 1,2,3-thia-diazole-4-thiolates
发明人：LEE VING J; CURRAN WILLIAM V
权利人:AMERICAN CYANAMID CO
摘要:Intermediates useful for synthesis of cephalosporins are disclosed, which intermediates are concerned with 1,2,3-thiadiazole-4-thiolates and the preparation of such thiolates.

专利号:JP-H09510206-A
优先权日:1994-03-07
标 题 :Compositions and methods used in the synthesis of oligonucleotides

专利号:US-4916237-A
优先权日:1986-07-08
标题:Substituted 1,2,3-thiadiazole-4-thiolates
发明人：LEE VING J; CURRAN WILLIAM V
权利人:AMERICAN CYANAMID CO
摘要:Intermediates useful for synthesis of cephalosporins are disclosed, which intermediates are concerned with 1,2,3-thiadiazole-4-thiolates and the preparation of such thiolates.

专利号:WO-9524413-A1
优先权日:1994-03-07
标 题 :Compositions and methods for use in the synthesis of oligonucleotides

专利号:EP-0749436-A1
优先权日:1994-03-07
标题:Compositions and methods for use in the synthesis of oligonucleotides